This experiment was designed to study the osteogenic potential of adding medical-grade resorbable calcium sulfate mixture to grafting materials for filling osseous defects. Twelve New Zealand rabbits were divided into an active group of 10 animals and a control group of 2 animals. The median condyle of each femur was drilled to create 8-mm-deep cavities. Active osseous defects consisted of 20 c...

Liver preparations from Syrian golden hamsters catalyze the metabolism of the pancreatic carcinogen N-nitroso-2,6-dimethylmorpholine largely to N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine (HPOP). This reaction is catalyzed by a mixed-function oxidase in the presence of reduced nicotinamide adenine dinucleotide phosphate and oxygen at a rate of 3.8 nmol/min/mg of protein, and it is inhibited by...

BACKGROUND Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage after blast injury. We have recently demonstrated that blast-triggered complement activation and cytokine release are associated with BINT. Here, we evaluated if administration of ...

Recent emerging market experience highlights that, in general, banking crises begin before currency crises. While empirical research is yet to establish the direction of causality, BOP crises have been interpreted and modeled only as consequence of financial sector meltdowns in the recent crisis literature. The evidence points out that equity and real estate prices decline well in advance of BO...

T he human metanephros is the direct precursor of the mature kidney: It begins to form in the fifth gestational week, when ureteric bud branches from the mesonephric duct; thereafter, renal mesenchyme condenses around the advancing bud and forms nephrons while the bud itself forms the ureter and collecting ducts. Perturbation of these events underlies the spectrum of disorders called congenital...

Purpose: Wilms' tumor is a childhood cancer of the kidney with an incidence of ∼1 in 10,000. Cooccurrence of Wilms' tumor with 2q37 deletion syndrome, an uncommon constitutional chromosome abnormality, has been reported previously in three children. Given these are independently rare clinical entities, we hypothesized that 2q37 harbors a tumor suppressor gene important in Wilms' tumor pathogene...

BACKGROUND Tachykinins (TK), such as substance P, and their neurokinin receptors which are ubiquitously expressed in the human urinary tract, represent an endogenous system regulating bladder inflammatory, immune responses, and visceral hypersensitivity. Increasing evidence correlates alterations in the TK system with urinary tract diseases such as neurogenic bladders, outflow obstruction, idio...