BACKGROUND During mesenchymal stem cell (MSC) conversion into adipocytes, the adipogenic cocktail consisting of insulin, dexamethasone, indomethacin and 3-isobutyl-1-methylxanthine not only induces adipogenic-specific but also genes for non-adipogenic processes. Therefore, not all significantly expressed genes represent adipogenic-specific marker genes. So, our aim was to filter only adipogenic...

Microarray analysis was used to investigate the lack of identified mammalian target of rapamycin (mTOR) pathway downstream genes to overcome cross-talk at non-muscle invasive high-grade (HG)-urothelial carcinoma (UC) of the bladder, gene expression patterns, gene ontology, and gene clustering by triple (p70S6K, S6K, and eIF4E) small interfering RNAs (siRNAs) or rapamycin in 5637 and T24 cell li...

OBJECTIVE Resident macrophages play an important role in atheromatous plaque rupture. The macrophage gene expression signature associated with plaque rupture is incompletely defined due to the complex cellular heterogeneity in the plaque. We aimed to characterise differential gene expression in resident plaque macrophages from ruptured and stable human atheromatous lesions. METHODS AND RESULT...

The energy available from the diet, which affects fat deposition in vivo, is a major factor in the expression of genes regulating fat deposition in the longissimus dorsi muscle. Providing high-energy diets to yaks might increase intramuscular fat deposition and fatty acid concentrations under a traditional grazing system in cold seasons. A total of fifteen adult castrated male yaks with an init...

Abstract Introduction Epicardial fat thickness or volume was found to be associated with cardiovascular disease (CVD). Our aim study the epicardial adipocyte-progenitors' markers and its association cholinergic adrenergic activity in patients disease. Materials methods We have included adipose tissue (EAT) biopsies from 29 underwent open-heart surgery. From 10 (69±5 years old, 31±8 kg/ m2, 40% ...

Bu çalışmada, Simental ırkı sığırlarda LEP-Sau3AI polimorfizm ve FABP4-Hin1I polimorfizmleri ile günlük laktasyon toplam süt verimi arasındaki ilişki araştırılmıştır. polimorfizminin belirlenmesi amacıyla yapılan polimeraz zincir reaksiyonu (PCR) sonunda 422 bp uzunluğunda bir PCR ürünü elde edilmiştir. için işlemi ise 399 Elde edilen genotipleri verimleri farklılığın önem kontrolü tek yönlü va...

Abstract. Although mesenchymal stem cells (MSCs) are the major source of adipocytes, adipogenesis is a highly complex process whose mechanisms driving adipocyte origin and development remain poorly understood. Previous findings by our group have shown that different MSCs from oral cavity displayed differential expression TET2, key regulator DNA methylation, during adipogenic induction. Therefor...