background: haemophilia a (ha) is an x-linked bleeding disorder caused by the absence or reduced activity of coagulation factor viii (fviii). coagulation factors are a group of related proteins that are essential for the formation of blood clots. the aim of this study was to genotype the coagulation factor viii gene mutations using inverse shifting pcr (is-pcr) in an iranian family with severe ...

extracellular ca 2+ concentration ([ca2+]o) may be one of the factors affecting atrial natriuretic factor (anf) release. in the previous studies, there are opposite reports about the effect of [ca2+]o on anf secretion. therefore, the effect of [ca2+]o depletion on anf secretion and gene expression was studied in the present research. isolated right atria from rats were perfused for 6 and 2 hour...

background and aims: infertility is a major problem during reproductive age. physical and psychological effects of infertility in women are problematic. the aim of this study was to determine the potential predictive factors of infertility, among women referring both public and private health centers in ilam province, western iran, in 2013. methods: in this cross-sectional study, 1013 women ref...

background:  gender  difference  has  been   reported  in stroke  risk factors  and  disease  history. the aim  of this study  was  to  compare  risk factors  and  the  severity  of ischemic stroke based  upon  modified rankin scale (mrs) and hospital mortality between two genders. methods: in a  cross-sectional  study, 341  patients  (44% males and 56% females with a mean age of 68.94 ± 12.74 ...

cytomegalovirus (cmv) infection is one of the most common infections that affects humans’ cardiovascular system. although the literature includes controversial evidence for any correlation between cmv infection and arterial atherosclerosis, the majority of studies, especially those with larger patient population and stronger data stand for such a relationship. however, the number of prospective...

800x600 background : hepatitis b and c infections have remained major global health burdens during the most recent century. the viral agents responsible for these diseases share common modes of transmission with human immunodeficiency virus (hiv) such as needle-sharing in iv drug abusers. coinfection of hepatitis b or c with hiv increases the rate of progression of chronic liver disease. given ...

background: determining the prevalence and risk factors of thrombocytopenia among neonates enables us to prevent the inevitable and sometimes irreversible complications. in this study we aimed to survey the frequency of thrombocytopenia and its demographic features and risk factors. materials and methods: in this cross sectional study the platelet counts of 364 neonates admitted to neonatal int...

conclusions the prevalence of both fv and fii variants are population based. iran is an ethnically diverse country. therefore, for a comprehensive analysis of a potential association of fv and/or fii mutations with stroke among iranian population, epidemiological studies could be conducted among different ethnic groups. patients and methods the study population consisted of 153 patients of diff...