نتایج جستجو برای: factor ii

تعداد نتایج: 1373784  

Journal: :Haematologica 2002
Alicia N Blanco Andrea Alcira Peirano Silvia Haydée Grosso Laura Cecilia Gennari Raúl Pérez Bianco María A Lazzari

BACKGROUND AND OBJECTIVES The development of neutralizing anti-factor VIII antibodies (a-fVIII) is a major clinical complication. Lupus anticoagulant (LA) might affect detection of a-fVIII, since both inhibitors may act on the same coagulation pathway. Our aim was to accomplish unequivocal detection and titration of a-fVIII even in the presence of LA. DESIGN AND METHODS We evaluated a-fVIII a...

Journal: :Blood 1998
A Zivelin N Rosenberg S Faier N Kornbrot H Peretz C Mannhalter M H Horellou U Seligsohn

The polymorphism G20210A in the 3' untranslated region of the prothrombin gene is associated with an increased level of factor II activity and confers a twofold to fivefold increase in the risk for venous thromboembolism. Among Caucasian populations, the prevalence of factor II G20210A heterozygotes is 1% to 6%, whereas in non-Caucasian populations it is very rare or absent. The aim of the pres...

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