Objective Globozoospermia is a rare syndrome with an incidence of less than 0.1% among infertile men. Researchers have recently identified a large deletion, about 200 kbp, encompassing the whole length of DPY19L2 or mutations in SPATA16 and PICK1 genes associated with globozoospermia. The aim of this study was to analyze the DPY19L2 gene deletion using polymerase chain reaction technique for th...

BACKGROUND Familial component is estimated to account for about 10% of ovarian cancer. However, the mode of inheritance of ovarian cancer remains poorly understood. The goal of this study was to investigate the inheritance model that best fits the observed transmission pattern of ovarian cancer among 7669 members of 1919 pedigrees ascertained through probands from the Gilda Radner Familial Ovar...

Robinson and colleagues refer to non-Alzheimer diagnoses of dementia. These less typical diagnoses pose complex problems for those with the disease and for their families, friends, and carers. When these forms of dementia affect younger people the problems can be even more challenging. When asking the question: “What constitutes best practice in early intervention?” we must acknowledge that peo...

Using a cross-sectional, exploratory design, this pilot study analyzed the relationships between familial history of breast cancer and psychological distress in order to evaluate who is more distressed and to assess the possible need for intervention. Coping style, social support, and family relations were investigated as potential moderators of these relationships. Participants were 45 women w...

Influence of social support on psychosocial dysfunction was studied in fifty newly diagnosed patients with major depression, using Social Support Scale (SSS) and Dysfunctional Analysis Questionnaire (DAQ) to measure social support and psychosocial dysfunction respectively. Total score on SSS did not affect the dysfunction. A positive relationship was observed between items of SSS relating to ca...

Familial factors and perinatal problems in idiopathic childhood epilepsy. D. H. Mellor, I. Lowit, and D. J. Hall introduced by G. Russell. Department of Child Health, University of Aberdeen. As part of a study of childhood epilepsy, 128 schoolchildren were identified who had been diagnosed as having epilepsy but who had no evidence of cerebral malformation, postneonatal brain damage, or abnorma...

patients and methods this cross-sectional study was performed on 1202 ms patients in farshchian hospital, hamadan, in 2013. all patients were diagnosed with definite ms. a questionnaire was used to gather information; demographic characteristics, medical history, signs and symptoms at onset, course of disease, relatives with ms, and degree and type of relationship were recorded. conclusions the...

Paragangliomas are neuroendocrine tumours and those occurring in the head and neck have well recognized familial association. Retroperitoneal paragangliomas are uncommon and we present two cases of familial malignant retroperitoneal paraganglioma. Review of the literature revealed marked differences in the incidence and malignant potential of familial and non-familial paraganglioma. In contrast...

extended abstract 1- introduction power is regarded as an important social variable when studying any social structure and institution. accordingly, distribution of power in family structure has a great importance and could affect many familial experiences such as development of personality, socialization, self-esteem, solidarity, satisfaction, happiness, etc. (mahdavi & saboori khosroshahi, 20...