نتایج جستجو برای: fas ligand

تعداد نتایج: 116939  

2003
Jean-Marie R. Saint-Remy Wim Janssens Vincent Carlier Bo Wu Luc VanderElst Marc G. Jacquemin

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
Z F Cheema S B Wade M Sata K Walsh F Sohrabji R C Miranda

The developing cerebral cortex undergoes a period of substantial cell death. The present studies examine the role of the suicide receptor Fas/Apo[apoptosis]-1 in cerebral cortical development. Fas mRNA and protein are transiently expressed in subsets of cells within the developing rat cerebral cortex during the peak period of apoptosis. Fas-immunoreactive cells were localized in close proximity...

Journal: :Journal of immunology 1998
T Kataoka M Schröter M Hahne P Schneider M Irmler M Thome C J Froelich J Tschopp

FLICE-inhibitory protein, FLIP (Casper/I-FLICE/FLAME-1/CASH/CLARP/MRIT), which contains two death effector domains and an inactive caspase domain, binds to FADD and caspase-8, and thereby inhibits death receptor-mediated apoptosis. Here, we characterize the inhibitory effect of FLIP on a variety of apoptotic pathways. Human Jurkat T cells undergoing Fas ligand-mediated apoptosis in response to ...

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