There are four hypotheses which have been advanced to explain the pathophysiology of severe and complicated malaria such as cerebral malaria. However, none of them adequately explains all the features of cerebral malaria in man. One such hypotheses is Disseminated Intravascular Coagulation (DIC). To determine whether this condition occurs in patients with uncomplicated malaria, the authors cond...

Since the first reports on surgical repair of macular holes, postoperative face-down posturing (FDP) has been part of the management regime. However, prone positioning is unpleasant for patients, and has adverse effects. Over the last decade some vitreoretinal surgeons have reduced the duration of FDP, or even abandoned it altogether. There have been few non-randomised, and even fewer randomise...

The force distribution problem (FDP) in robotics requires the determination of multiple contact forces to match a desired net contact wrench. For the double support case encountered in humanoids, this problem is underspecified, and provides the opportunity to optimize desired foot centers of pressure (CoPs) and forces. In different contexts, we may seek CoPs and contact forces that optimize act...

BACKGROUND The Humphrey field analyser (HFA), Humphrey-Zeiss frequency doubling perimeter, and the Medmont automated perimeter (MAP) are three commonly used automated perimeters with threshold achromatic methodologies. Visual field loss may be detected earlier with strategies that target cell lines with reduced redundancy or which suffer selective damage. METHOD To compare these three perimet...

Residuals of a conventional plate adjustment of 5,687 plates of the Second Cape Photographic Catalogue (CPC2) using the Southern Reference Star (SRS) Catalog were analyzed to search for systematic errors depending on the location of the star images on the plate. Even after correcting for third order optical distortion, such coordinate depending systematic errors, hereafter called field distorti...

Consider the multiple testing problem of testing m null hypotheses H1, . . . ,Hm, among which m0 hypotheses are truly null. Given the P-values for each hypothesis, the question of interest is how to combine the P-values to find out which hypotheses are false nulls and possibly to make a statistical inference onm0. Benjamini and Hochberg proposed a classical procedure that can control the false ...

A fundamental problem for peer-to-peer systems is to maintain connectivity while nodes are leaving, i.e., the nodes requesting to leave the peer-topeer system are excluded from the overlay network without affecting its connectivity. There are a number of studies for safe node exclusion if the overlay is in a well-defined state initially. Surprisingly, the problem has not been formally studied y...

We recently examined the extent to which motor units of digit flexor muscles receive common input during multidigit grasping. This task elicited moderate to strong motor-unit synchrony (common input strength, CIS) across muscles (flexor digitorum profundus, FDP, and flexor pollicis longus, FPL) and across FDP muscle compartments, although the strength of this common input was not uniform across...

Flexor digitorum profundus (FDP), the sole flexor of the fingertips, is critical for tasks such as grasping. It is a compartmentalized multitendoned muscle with both neural and mechanical links between the fingers. We determined whether voluntary activation (VA), the level of neural drive to muscle, could be measured separately in its four compartments, whether VA differed between the fingers, ...

AIMS To examine whether coagulation-fibrinolysis in late pregnancy in women with twin pregnancies is more pronounced than in women with singleton pregnancies. PATIENTS AND METHODS The plasma levels of D-dimer, fibrinogen/fibrin degradation products (FDP), and fibrinogen, the platelet count, and the antithrombin activity were assessed from 3 weeks before delivery until postpartum day 7 in 48 w...