Abstract Background The levels of tryptophan (TRP) metabolites such as kynurenine (KYN), kynurenic acid (KYNA), quinaldic acid, 3-hydrocynynene, anthranilic picolinic (PA) and xanthurenic were determined systematically in inflammatory bowel disease (IBD). Previous studies found a negative correlation with TRP IBD activity. However, there is no data about serum their severity IBD. We aimed to de...

Inflammatory bowel disease (IBD) is a chronic disease mostly involved with intestine with unknown etiology. Diagnosis, evaluation of severity, and prognosis are still present as challenges for physicians. An ideal biomarker with the characters such as simple, easy to perform, noninvasive or microinvasive, cheap, rapid, and reproducible is helpful for patients and clinicians. Currently biomarker...

Esophageal Crohn’s disease (CD) is rare. We present a young girl with dysphagia, weight loss and retrosternal pain due to esophageal CD. Diagnosis was only confirmed after repeated esophageal biopsies and an additional ileocolonoscopy. Abdominal ultrasound and fecal calprotectin did support the diagnosis of CD. Treatment by exclusive enteral feeding, temporary oral viscous budesonide, esomepraz...