The risk of structural heart disease is significantly higher in twin pregnancies than in singleton pregnancies, but the concordance rate has been found to be relatively low, even in monochorionic pregnancies. This is the first report of a monochorionic twin pregnancy concordant for hypoplastic left heart syndrome (HLHS), the diagnosis having been made by fetal echocardiography at 15 weeks' gest...

Ebstein’s anomaly accounts for 0.5% of all congenital heart diseases. The condition is characterized by >8 mm/m2 displacement of the septal and posterobasal tricuspid leaflets toward the apex of the right ventricle (RV). This causes “atrialization” of the RV inflow tract, with decreased size of the RV and right atrial (RA) dilatation. The anterior valve is rarely displaced, but tends to be larg...

Fetal echocardiography in the 32nd week of gestation showed cardiac tumor and pericardial effusion. The pericardial effusion gradually increased, and cardiac function was impaired by cardiac tamponade. Cardiotocography showed fetal distress. Emergent cesarean section was performed. Cardiac tamponade resulted in respiratory failure after birth. Artificial ventilation and pericardiocentesis were ...

Abstract Background Congenital heart disease (CHD) is the most common birth defect, affecting approximately eight per thousand newborns. Between one and two neonates have congenital cardiac lesions that require immediate post-natal treatment to stabilize circulation, management of these patients in particular has been greatly enhanced by prenatal detection. The antenatal diagnosis CHD made poss...

BACKGROUND Newborns with hypoplastic left heart syndrome (HLHS) or right heart syndrome or other malformations with a single ventricle physiology and associated hypoplasia of the great arteries continue to be a challenge in terms of survival. The vast majority of these forms of congenital heart defects relate to abnormal morphogenesis during early intrauterine development and can be diagnosed a...

Pulmonary hypertension may occur in the fetus in the presence of constriction of the ductus arteriosus. The feasibility of detection and quantitation of fetal ductal constriction by Doppler echocardiography was assessed in an animal preparation in which ductal constriction was created in the fetal lamb with a variable ligature causing varying degrees of fetal pulmonary hypertension (fetal pulmo...

OBJECTIVE To evaluate the incidence of fetal dextrocardia, associated cardiac and extracardiac malformations, and outcome. DESIGN Retrospective echocardiographic study. SETTING Two tertiary centres for fetal cardiology. PATIENTS 81 consecutive fetuses with a fetal dextrocardia presenting at Guy's Hospital, London, between 1983 and 2003 and at Hôpital Robert Debré, Paris, between 1988 and ...

Objective: To evaluate the incidence of fetal dextrocardia, associated cardiac and extracardiac malformations, and outcome. Design: Retrospective echocardiographic study. Setting: Two tertiary centres for fetal cardiology. Patients: 81 consecutive fetuses with a fetal dextrocardia presenting at Guy’s Hospital, London, between 1983 and 2003 and at Hôpital Robert Debré, Paris, between 1988 and 20...

surgery for heart diseases during pregnancy, especially necessitating cardiopulmonary bypass, is believed to trigger maternal and fetal risks and should be performed only when medical therapy has been unsuccessful to alleviate the cardiac decompensation. a 33-year-old pregnant woman in her 33rd week of gestation was admitted to our hospital. she had rheumatic mitral valvular stenosis and had un...

The purpose of this study is to provide standard echocardiographic and morphometric data for normal mouse valve structure and function from late fetal to aged adult stages. Cross-sectional, two-dimensional and Doppler transthoracic echocardiography was performed in C57BL6 mice anesthetized with 1% to 2% isoflurane at embryonic day 18.5 (late fetal), 10 days (neonate), 1 mo (juvenile), 2 mo (you...