The activity of cytochrome P450 enzymes depends on the enzyme NADPH P450 oxidoreductase (POR). The aim of this study was to investigate the activity of the equine CYP3A94 using a system that allows to regulate the POR protein levels in mammalian cells. CYP3A94 and the equine POR were heterologously expressed in V79 cells. In the system used, the POR protein regulation is based on a destabilizin...

Recent (<5 Ma) Hawaiian volcanoes define two sub-parallel spatial trends, Loa and Kea. Despite the short distance ( 30 km) between adjacent volcanoes on these trends, most of the Loa-trend shield lavas are geochemically distinct from most of the Kea-trend shield lavas. These geochemical differences arise from small amounts of the LOA component in the source of Loa-trend shield lavas. This compo...

Actual endotoxin levels in each batch are usually measured at < 0.13 EU/ml. Unlike manufacturers of other density gradient media, Axis-Shield do not have to offer special, more expensive, low endotoxin-containing products; all Axis-Shield Density Gradient Media have always been, and continue to be, produced to the same high rigorous standards. For every batch produced, a Certificate of Analysis...

Most of internal combustion engines have one or two heat shields that have been installed on the exhaust manifold to avoid the heat transfer to upper parts of the engine such as the valve cover. In some engines, this part fails due to the fracture and causes engine noise and other failures in the engine. In this paper, the failure of a heat shield due to vibrational loads of the engine has been...

In this paper we analyze the effectiveness of dynamic artificial diversity, i.e., artificial diversity in which the subject of the diversity is re-randomized periodically. We refer to a mechanism that implements dynamic diversity as a Metamorphic Shield since this mechanism applies metamorphosis to the system’s attack surface to try to shield the system from certain attacks. Contrary to intuiti...

The cyclotron at our hospital has a self-shield of boron-containing water. The amount of induced radioactivity in the boron-containing water shield of a compact medical cyclotron has not yet been reported. In this study, we measured the photon and neutron dose rates outside the self-shield during cyclotron operation. We estimated the induced radioactivities of the boron-containing water used fo...

The use of trademarks or names of manufacturers in this report is for accurate reporting and does not constitute an ocial endorsement, either expressed or implied, of such products or manufacturers by the National Aeronautics and Space Administration. Summary The space program is faced with two dicult radiation protection issues for future long-term operations. First, retrot of shield material ...

OBJECTIVE To solve the complicated wires and battery maintenance problems in the application of wearable computing for biomedical monitoring, the electromyography (EMG) measurement system using conductive fabric for power supply and electric shield for noise reduction is proposed. MATERIAL AND METHODS The basic cable-free network system using conductive fabric, named as "TextileNet" is develo...

Introduction: A number of terrestrial analog studies have focused on characterizing individual lava flows [e.g., 3, 6-7]. Morphometric and compositional information from these features can be used to infer the rheological properties of similar lava flows, the timing and duration of the eruptions episodes, the depth of the magma chambers [2, 12-14], and even the eruptive and emplacement history ...

This paper presents a computer simulation of reflected and scattered laser radiation for calculating the angle of laser shields performed with the Laser Shield Solver computer program. The authors describe a method of calculating the shield angle for laser shields which protect workers against reflected and scattered laser radiation and which are made from different materials. The main assumpti...