Silk fibroin, a widely used natural biopolymer, presents remarkable flexibility and biodegradability, making it of great interest as polymer matrix for functional composite materials. Herein, composites silk nanofibrils metal–organic framework (MOF) nanosheets were successfully fabricated by coincubation coassembly process. Under heat incubation, fibroin self-assembled into one-dimensional nano...

BACKGROUND The aim of this study was to characterize the efficacy of nano-hydroxyapatite-coated silk fibroin constructs as a scaffold for bone tissue engineering and to determine the osteogenic effect of human dental pulp and periodontal ligament derived cells at an early stage of healing in rabbits. 3D silk fibroin constructs were developed and coated using nano-hydroxyapatite crystals. Dental...

BACKGROUND Current treatment of inflammatory bowel disease is based on the use of immunosuppressants or anti-inflammatory drugs, which are characterized by important side effects that can limit their use. Previous research has been performed by administering these drugs as nanoparticles that target the ulcerated intestinal regions and increase their bioavailability. It has been reported that si...

The silk road: By employing silk fibroin as a binder between graphene oxide films and aluminum foil for a facile, highly localized reduction process, conductive paper is reinvented. The flexible, robust biographene papers have high toughness and electrical conductivity. This electrochemical written-in approach is readily applicable for the fabrication of conductive patterned papers with complex...

Biocompatible materials have received increased interest due to their combination of unique physical, chemical, and biological properties and their potential in the fields of drug delivery, medical treatments, and other biological applications. Among the natural polymers, silkworm silk fibroin has been of interest for its use in textiles but also in consumer products such as cosmetic creams, lo...

Skin wounds are one of the most common injuries for human body; they can lead to an infection and cause tissue necrosis even life-threatening injuries. Therefore, it is urgent task develop skin scaffold materials meet various needs restoring skin’s structural integrity. In this research, kaolinite nanotubes silver nanowires co-doped silk fibroin gelatin composite porous fiber films were fabrica...

The development of simple and versatile methods for the deposition biocompatible coatings to protect or functionalize a range materials with different shapes is an important challenge. In this study, versatile, room-temperature process presented silk fibroin on viz., glass, polyethylene terephthalate, Ti alloy, poly(dimethylsiloxane). Coating thin films achieved using atmospheric plasma torch, ...

PURPOSE This study evaluated powdered burn wound dressing materials from wild silkworm fibroin in an animal model. METHODS Fifteen rats were used in this experiment. Full-thickness 2×2 cm burn wounds were created on the back of rats under anesthesia. In the two experimental groups, the wounds were treated with two different dressing materials made from silkworm fibroin. In the Control Group, ...

An octapeptide, GAGAGAGY, was obtained by a novel method, i.e. hydrolysing Bombyx mori silk fibroin. Afterward, a dodecanoic acid-peptide conjugation was synthesized. This amphiphile assembled into cylindrical nanofibers of planar β-sheets at pH 9 and twisted β-sheets at pH 4.

Silk fibroin exists in a number of different states, such as silk I and silk II, with different properties largely defined by differences in secondary structure composition. Numerous attempts have been made to control the transitions from silk I to silk II in vitro to produce high-performance materials. Of all the factors influencing the structural compositions, pH and some metal ions play impo...