Several studies have previously reported synergistic effects between vancomycin and a given beta-lactam or a given aminoglycoside against methicillin-resistant Staphylococcus aureus (MRSA) strains. The aim of our study was to exhaustively compare the effects of different combinations of a beta-lactam, vancomycin, and/or an aminoglycoside against 32 clinical MRSA strains with different aminoglyc...

Combination therapy of flucytosine (5FC) with other antifungal agents could be of use for the treatment of invasive aspergillosis. However, interpretation of the results of in vitro interactions is problematic. The fractional inhibitory concentration (FIC) index is the most commonly used method, but it has several major drawbacks in characterizing antifungal drug interaction. Alternatively, a r...

Multi-FPGA systems have been receiving a lot of attention as low cost and energy efficient system for Multi-access Edge Computing (MEC). For such purpose, bare-metal multi-FPGA called FiC (Flow-in-Cloud) is under development. In this paper, we introduce the multi FPGA cluster which applied partial reconfiguration (PR) design flow to support online user defined accelerator replacement while exec...

The combination effect of miconazole with polygodial against Candida albicans was investigated by an in vitro checkerboard method. Isobolograms, fractional inhibitory concentration (FIC), and fractional fungicidal concentration (FFC) indices were used for evaluating the interaction between compounds combined. The combination of miconazole with polygodial exhibited strong synergism on both fungi...

BACKGROUND The indiscriminate use of antibiotics in the treatment of infectious diseases can increase the development of antibiotic resistance. Therefore, there is a big demand for new sources of antimicrobial agents and alternative treatments for reduction of antibiotic dosage required to decrease the associated side effects. OBJECTIVES In this study, the synergistic action of aminoglycoside...

Effective estimation of the salience of environmental stimuli underlies adaptive behavior, while related aberrance is believed to undermine rational thought processes in schizophrenia. A network including bilateral frontoinsular cortex (FIC) and dorsal anterior cingulate cortex (dACC) has been observed to respond to salient stimuli using functional magnetic resonance imaging (fMRI). To test the...

The emergence of multidrug-resistance (MDR)—New Delhi metallo-beta-lactamase (NDM)-producing microorganisms—has become a serious concern for treating such infections. Therefore, we investigated the effective antimicrobial combinations against multidrug-resistant New metallo-beta-lactamase-producing strains Enterobacterales. tests were carried out using 2D(two-dimensional) checkerboard method. O...

Toplum Ruh Sağlığı Merkezleri (TRSM), ağır ruhsal rahatsızlığı olan hastaların yaşadıkları ortamda takip ve tedavilerinin yapıldığı hastanelere entegre birimlerdir. Bu birimlerde görevli ergoterapistlerce tedavi sürecinde ihtiyaç, istek becerilerine uygun olarak uygulanan aktivitelerden biri de bitki terapi bahçeleridir.
 araştırma, Türkiye’deki farklı bölgelerden seçilen 54 TRSM’de gerçek...

Resumo O estudo se refere à implementação do Programa Nacional de Acesso ao Ensino Técnico e Emprego (Pronatec), criado pela Lei n° 12.513/2011, com os objetivos declarados expandir interiorizar a política educação profissional tecnológica, estimular articulação dessa as políticas geração emprego ampliar oportunidades educacionais dos trabalhadores. programa também propôs melhorar qualidade ens...

Some of the most basic questions about the history of life concern evolutionary trends. These include determining whether or not metazoans have become more complex over time, whether or not body size tends to increase over time (the Cope-Depéret rule), or whether or not brain size has increased over time in various taxa, such as mammals and birds. Despite the proliferation of studies on such to...