The partial phase behavior of systems composed of lecithin/isopropyl myristate (IPM)/water or ketorolac tromethamine (KT) solutions (2.5, 5, 10 and 50% w/w) at various lecithin/IPM weight ratios (km) have been investigated by the construction of phase diagrams. A commercially available soybean lecithin (namely, Epikuron 200, phosphatidylcholine purity greater than 95%) was used in this study. P...

Purpose To establish the lowest concentration of a solution of dipalmitoyl phosphatidylcholine which can be detected in vitro by proton magnetic resonance spectroscopy at 1.5T. Background Pulmonary surfactant is a phospholipid and protein mixture which is normally excreted by the fetal lungs from around 23 weeks gestation and plays a vital role after birth in reducing surface tension at the alv...

A patient with sea-blue histiocytosis in spleen and bone marrow with an accompanying hyperlipidaemia is described. The hyperlipidaemia was due to an increase in "free" cholesterol, lecithin, and triglycerides. Despite these findings lecithin-cholesterol acyl transferase activity was normal. Although the precise biochemical defect was not identified, there was a failure of transport of cholester...

THE latest work on the isoelectric point of lecithin is that of Price and Lewis [1933] investigating the macrocataphoresis oflecithin dispersions. As in previous work it was noted that the electrical properties of lecithin show a gradual change with the time. Thus the (presumably negative) mobility of a freshly prepared dispersion "increased, at given PHX with the age of the lecithin used, reac...

The relation between the choline containing surfactant phospholipids lecithin and sphingomyelin in amniotic fluid and fetal lung maturity is well established. An enzymatic method that had been automated and optimised for use on a centrifugal analyser was used to measure the total choline containing phospholipids in amniotic fluid. The total time taken for this assay was 10 minutes. The results ...

The relation between the choline containing surfactant phospholipids lecithin and sphingomyelin in amniotic fluid and fetal lung maturity is well established. An enzymatic method that had been automated and optimised for use on a centrifugal analyser was used to measure the total choline containing phospholipids in amniotic fluid. The total time taken for this assay was 10 minutes. The results ...

Presented in part at the American Gastroenterological Association Meeting, San Francisco, California, May, 1974, and in part at the Bile Acid Meeting (III), Freiburg, Germany, June, 1974. Received for publication 8 April 1974 and in revised form 9 September 1974. lecithin. These data provide evidence that (a) biliary lecithin and cholesterol are derived from a microsomal subpool regulated by th...