Neuroscientists formulate very different hypotheses about the nature of neural code. At one extreme, it has been argued that neurons encode information in relatively slow changes of individual spikes arriving rates (rates codes) and the irregularity in the spike trains reflects noise in the system, while in the other extreme this irregularity is the code itself (temporal codes) thus the precise...

A population of firing neurons is expected to carry information not only by mean firing rate but also by fluctuation and synchrony among neurons. In order to examine this possibility, we have studied responses of neuronal ensembles to three kinds of inputs: mean-, fluctuation-and synchrony-driven inputs. The generalized rate-code model including additive and multiplica-tive noise (H. Hasegawa, ...

In S2 Fig., the second and third rows of firing rate maps in panel A are swapped and incorrectly labeled "arena frame" and "room frame" respectively. Instead, the second row should be labeled “room frame” and the third row should be labeled “arena frame”. Also, the spatial coherence numbers for the fourth row of firing rate maps in panel A were incorrectly duplicated from the first row. Please ...

Two compartmental models of spinal alpha motoneurons were constructed to explore the relationship between background firing rate and response to an excitatory input. The results of these simulations were compared with previous results obtained from human motoneurons and discussed in relation to the current model for repetitively firing human motoneurons. The morphologies and cable parameters of...

The dynamics of microelectrode local field potentials from cortical slice cultures shows critical behavior. A desirable feature of criticality is that information transmission is optimal in this state. We explore a biologically plausible neural net model that can dynamically converge on criticality and that can return to criticality if perturbed away from it. Our model assumes the presence of a...

The discharge properties of single neuronal units in the putamen, caudate nucleus, and globus pallidus were studied in awake primates. The effects of restricted deafferentation of the striatum were determined by recording single unit activity in animals with unilateral ablation of areas 4 and 6 of Brodmann. The most striking change was on the regularity of unit firing in the putamen. Units in t...

We have examined extracellularly the firing pattern of neurons in the cat external cuneate nucleus and in the human main cuneate nucleus, focusing upon both the spontaneous firing patterns and its modification by natural stimulation. Many of these neurons exhibit stereotyped doublet or burst firing patterns, e .g., the interval between the spikes might be 1 .0 + 0 .1 msec in a given cell . For ...

For the past five decades there has been wide acceptance of a relationship between the firing rate of motor units and the afterhyperpolarization of motoneurons. It has been promulgated that the higher-threshold, larger-soma, motoneurons fire faster than the lower-threshold, smaller-soma, motor units. This relationship was based on studies on anesthetized cats with electrically stimulated motone...

Point neuron models with a Heaviside firing rate function can be ill-posed. That is, the initial-condition-to-solution map might become discontinuous in finite time. If a Lipschitz continuous but steep firing rate function is employed, then standard ODE theory implies that such models are well-posed and can thus, approximately, be solved with finite precision arithmetic. We investigate whether ...