Dysregulation of the cell proliferation has been implicated in the pathophysiology of a number of diseases. Cellular senescence limits proliferation of cancer cells, preventing tumorigenesis and restricting tissue damage. However, the role of cellular senescence in proliferative nephritis has not been determined. The proliferative peak in experimental rat nephritis coincided with a peak in E2A ...

FLASH (FLICE-associated huge protein or CASP8AP2) is a large multifunctional protein that is involved in many cellular processes associated with cell death and survival. It has been reported to promote apoptosis, but we show here that depletion of FLASH in HT1080 cells by siRNA interference can also accelerate the process. As shown previously, depletion of FLASH halts growth by down-regulating ...

Flash memory affects not only storage options but also query processing. In this paper, we analyze the use of flash memory for database query processing, including algorithms that combine flash memory and traditional disk drives. We first focus on flash-resident databases and present data structures and algorithms that leverage the fast random reads of flash to speed up selection, projection, a...

There has been an increase in the occurrence of sudden local flooding of great volume and short duration caused by heavy or excessive rainfall intensity over a small area, which presents the greatest potential danger threat to the natural environment, human life, public health and property, etc. Such flash floods have rapid runoff and debris flow that rises quickly with little or no advance war...

Constructing flash memory based storage, FTL (Flash Translation Layer) manages mapping between logical address and physical address. Since FTLwrites everydata to new region by itsmappingmethod, the previous data is not overwritten by new write operation. When a journaling file system is set up upon FTL, it duplicates data between the journal region and its home location for the file system cons...

Flash storage is making inroads into data centers, enabling a new class of applications that require persistence as well as extreme performance. Clusters of flash can satisfy millions of IOs per second at submillisecond latencies while consuming significantly less power per IO than disk clusters. Unfortunately, current designs for scalable storage systems are predicated on the properties of har...

-Flash memory has more capacity and less weight. It makes it more suitable for electronic media. Electronics such as tablet PC and smart phones use NAND flash memory as a secondary storage because it has many attractive features such as small size, fas t access speeds, and light weight. However, it has shown limited success in its battle against the hard disk, due to intrinsic weak points of: e...

Contrary to intuition, host-side flash caches can degrade performance rather than improve it. With flash write operations being expensive, cache hit-rates need to be relatively high to offset the overhead of writes. Otherwise, the end-to-end performance could be worse with flash cache. We believe that some lessons learnt from multi-tiered storage systems can be applied to flash cache management...

Host-side flash storage opens up an exciting avenue for accelerating Virtual Machine (VM) writes in virtualized datacenters. The key challenge with implementing such an acceleration layer is to do so without breaking live VM migration which is essential for providing distributed resource management and high availability. High availability also powers-on VMs on new host when the previous host cr...

In neurosurgical procedures that may cause visual impairment in the intraoperative period, the monitoring of flash visual evoked potential (VEP) is clinically used to evaluate visual function. Patients are unconscious during surgery under general anesthesia, making flash VEP monitoring useful as it can objectively evaluate visual function. The flash stimulus input to the retina is transmitted t...