The adenylate cyclase system in a plasma membrane-rich fraction termed “ghosts” from rat adipocytes is activated by epinephrine, adrenocorticotropic hormone, glucagon, and secretin, and is also stimulated in the presence of fluoride ion. Studies of the temperature dependency of activation by these agents showed that whereas hormonal activation occurs down to lo”, activation by fluoride ion is m...

Background: Waning controversy over fluoride and water fluoridation is rekindling with the findings released from certain fluoride studies which reported an inverse association between fluoride exposure and intelligence. Objective: To assess the relationship between exposure to different drinking water fluoride levels and children's Intelligence Quotient (IQ) among 13-15 year old school childre...

BACKGROUND Water fluoride level is unknown in many regions of Iran. Besides, only few non-controlled studies world-wide have assessed the effect of water fluoride on dental fluorosis and caries. We aimed to measure the fluoride level of 76 water supplies in 54 cities and evaluate the effect of fluoride on dental caries and fluorosis in a large multi-project study. MATERIALS AND METHODS In the...

Fluoridation of drinking water and dental products prevents dental caries primarily by inhibiting energy harvest in oral cariogenic bacteria (such as Streptococcus mutans and Streptococcus sanguinis), thus leading to their depletion. However, the extent to which oral and gut microbial communities are affected by host fluoride exposure has been underexplored. In this study, we modeled human fluo...

The present study was designed to investigate the toxic effects (evaluated as histopathological changes) of sodium fluoride on the kidney in two consecutive generations of NMRI mice. An attempt to correlate the toxicity with the urinary elimination of fluoride has been made, as urinary fluoride excretion has been widely used as an indicator of fluoride intake and exposure. Six mixed (males and ...

ABSTRACT: Relationship between bone fluoride content, pathological change in bone of aborted fetuses and maternal fluoride level was studied in 46 pregnant women and their inducedly-aborted fetuses. Results showed fluoride content in fetal femur averaged 368.2 micrograms(ug)/g, and 41.4% of the bone with pathological change. Fluoride levels in maternal urine and amniotic fluid and fluoride cont...

Rats given 4 mg. fluoride/kg./day for eight days excreted more calcium and phosphorus and retained less than the controls. In bone ash from rats given different fluoride doses for 40 days the calcium and phosphorus were maximal after a total dose of about 250 ,tg. fluoride/rat, but fell to subnormal levels after higher doses. The calcium and phosphorus levels in bone ash from rats given 750 pg....

Abstract. In Thailand, the consumption of soy milk products is common but there is limited data about their fluoride content. The purpose of this study was to es- timate the fluoride content of soy milk products available in Thailand. Fluoride content was determined for 76 brands of soy milk using a F-ion-specific electrode. The fluoride concentrations ranged from 0.01 to 3.78 μg/ml. The fluori...

background: surface microhardness is a physical property which access the effect of chemical and physical agents on hard tissues of teeth, and a useful way to examine the resistance of fluoride treated enamel against caries. the purpose of this study was to evaluate microhardness of enamel following ph-cycling through demineralization and remineralization using suspensions of dentifrices with d...

Adsorption is one important technique in fluoride removal from aqueous solutions. The viability of adsorption techniques is greatly dependent on the development of adsorptive materials. A large number of materials have been tested at a fluoride concentration greater than 2 mg/l, and the lowest limit for fluoride reduction by them is about 2 mg/l. Decreasing the fluoride concentration to less th...