Glucosinolates, a class of secondary metabolites from cruciferous plants, are derived from amino acids and have diverse biological activities, such as in biotic defense, depending on their side chain modification. The first structural modification step in the synthesis of aliphatic (methionine-derived) glucosinolates-S-oxygenation of methylthioalkyl glucosinolates to methylsulfinylalkyl glucosi...

Molecular cruciforms are X-shaped systems in which two conjugation axes intersect at a central core. If one axis of these molecules is substituted with electron-donors, and the other with electron-acceptors, cruciforms' HOMO will localize along the electron-rich and LUMO along the electron-poor axis. This spatial isolation of cruciforms' frontier molecular orbitals (FMOs) is essential to their ...

Breast cancer is a complicated disease that it is accompanied by different symptoms. Diagnosis of this disease is performed by various techniques. Using Radiopharmaceuticals is a new method to diagnose the said tumors. [18F]-FPTT is one of these nuclear medicines for detection of breast cancer. It seems that the binding of the title radiopharmaceutical to the progesterone receptor is...

background: prediction of interaction sites within the membrane protein complexes using the sequence data is of a great importance, because it would find applications in modification of molecules transport through membrane, signaling pathways and drug targets of many diseases. nevertheless, it has gained little attention from the protein structural bioinformatics community. methods: in this stu...

objective: parental self-efficacy is associated with increasing mental health in children. there is a paucity of research in iran on the role of parental self-efficacy in increasing mental health status of children. in this preliminary study, we studied the effectiveness of the world health organization international child development program (2002) for children aged 3 years and younger in incr...

the interaction of brilliant green with herring sperm dna was investigated in detail by spectrometric methods in γ-cyclodextrin systems. on the condition of physiological ph, brilliant green prefers to form the 1:1 inclusion complex with γ-cyclodextrin.all the evidences indicated that the binding modes between γ-cyclodextrin-brilliant green and dna were grooving binding and partial non-classica...

introduction: interaction between drugs represents a major clinical concern for health care professionals and their patients. patients affected by both type 2 diabetes and epilepsy may be prescribed pioglitazone and an anti-epileptic drug such as phenytoin  concurrently. the aim of this study was to consider the interaction of pioglitazone with phenytoin in an experimental model. according to t...

objective:the purpose of this study was to investigate the effects of piroxicam co-administration with ethanolic stem-bark extract of khaya senegalensis on biomarkers of oxidative stress and gastro-toxicity in wistar rats. materials and methods: thirty healthy male and female albino wistar rats (190-220 g) were grouped into six (n = 5) with designated treatments including: normal saline, piroxi...

abstract- the effects of iron (fe) and zinc (zn) treatments on the growth and nutrient composition of chickpea were studied in a greenhouse experiment arranged in a completely randomized design. while the application of fe decreased mean shoot dry weight of chickpea, that of zn had no significant effect on chickpea shoot dry weight. increasing fe levels drastically decreased mn concentration an...

the ammi and sreg gge   are among the models that effectively capture the additive and multiplicative components of genotype × environment interaction (gei) and provide meaningful interpretation of multi-environment trials’ data set in the breeding programs. the objective of this study was to assess the effect of gei on grain yield of barely advanced lines and exploit the positive gei effect us...