Serum response factor (SRF) is a transcription factor of the MADS box family. SRF is involved in various cellular processes such as expression of immediate early and tissue-specific genes, cell proliferation, differentiation and apoptosis. The expression of SRF in papillary thyroid carcinoma (PTC) and its role have not been investigated, forming the basis for this study. Surgical specimens of 6...

OBJECTIVE To investigate the expression of connexin 43 (Cx43) in benign vs malignant thyroid tissue for potential use as a diagnostic marker. DESIGN Retrospective study. SUBJECTS Thyroid specimens were obtained from 50 patients who underwent partial or total thyroidectomy at the New York Eye and Ear Infirmary, New York, New York, between 1999 and 2007. They included goiter (n = 5), follicul...

The objective of the present study was to compare the effects of isotretinoin 9-cis (RA9-cis) as a post-surgery treatment of thyroid carcinoma to a traditional treatment (doxorubicin) and no treatment. Owners who did not want their dogs to receive treatment were placed into the control group A (GA; n=10). The remaining dogs were randomly placed into either group B (GB; n=12) and received doxoru...

BACKGROUND Distant metastasis from differentiated thyroid carcinoma at presentation is rare and isolated liver metastasis on presentation is almost unknown. We report a case of primary follicular carcinoma of the thyroid with isolated liver metastasis at presentation. CASE PRESENTATION A 65-year-old man of Kashmiri origin presented to our tertiary referral center with obstructive jaundice; he...

The aim of the study: present study is to evaluate accuracy fine needle aspiration cytology (FNAC) thyroid swellings and correlate with histopathological findings avoid unnecessary surgeries for benign lesions.
 Methods: this a prospective study. A total 55 cases were studied in Department Pathology at A.C.S Medical College Hospital. Fine was done correlated examination. Sensitivity, speci...