In this article we introduce differential evolution based multiple vector prototype classifier (shortly MVDE). In this method we extend the previous DE classifier so that it can handle several class vectors in one class. Classification problems which are so complex that they are simply not separable by using distance based algorithms e.g. differential evolution (DE) classifier or support vector...

MOTIVATION The classification methods typically used in bioinformatics classify all examples, even if the classification is ambiguous, for instance, when the example is close to the separating hyperplane in linear classification. For medical applications, it may be better to classify an example only when there is a sufficiently high degree of accuracy, rather than classify all examples with dec...

The nearest shrunken centroid classifier uses shrunken centroids as prototypes for each class and test samples are classified to belong to the class whose shrunken centroid is nearest to it. In our study, the nearest shrunken centroid classifier was used simply to select important genes prior to classification. Random Forest, a decision tree based classification algorithm, is chosen as a classi...