نتایج جستجو برای: formulation excipients
تعداد نتایج: 112735 فیلتر نتایج به سال:
Description: Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing rev...
fines excipients as “substances, other than the active drug substance of finished dosage form, which have been appropriately evaluated for safety and are included in a drug delivery system to either aid the processing of the drug delivery system during its manufacture; protect; support; enhance stability, bioavailability, or patient acceptability; assist in product identification; or enhance an...
Melatonin a hormone is major product of the pineal gland. Alprazolam an anti-anxiety drug that belongs to benzodiazepines category. The quantity alprazolam and melatonin had been calculated by use regression equation responses were measured at 277 nanometers wavelength using above-mentioned conditions RP-HPLC simultaneous estimation has developed method determined for validation. was estimated ...
The present study was undertaken with an aim to formulate develop and evaluate Trimetazidine HCL extended release matrix tablets using different polymers as retarding agent. Pre formulation done initially results directed for the further course of formulation. Based on studies batches were prepared selected excipients. Powders evaluated tests Angle repose, Bulk density, tapped compressibility i...
The Benign Prostatic Hyperplasia is one of the common old age problem and alpha adrenoreceptor blockers are commonly used for symptomatic relief. Tamsulosin HCl selective 1A blocker with better tolerability profile once daily dosing advantage. present study was under taken to establish compatibility a number excipients by using thermo analytical technique viz Thermogravimetry (TG) differential ...
INTRODUCTION Many drugs are unavailable in suitable oral paediatric dosage forms, and pharmacists often have to compound drugs to provide paediatric patients with an acceptable formulation in the right dose. Liquid formulations offer the advantage of dosing flexibility and ease of administration to young patients, but drug substances often show poor aqueous solubility. The objective of this wor...
this paper describes two rapid, sensitive and specific methods for the determination of fulvestrant in pharmaceutical preparations by high performance liquid chromatography (hplc) and linear sweep voltammetry (lsv). hplc method was used to study the degradation behaviour. fulvestrant was subjected to degradation under the conditions of hydrolysis (acid and alkali), oxidation (30% h2o2). the lin...
Abstract Background Pharmaceutical excipient development is an extensive process requiring a series of pre-formulation studies to evaluate their performance. The present study compares the conventional compaction and compression with artificial intelligence (AI) modeling predict performances thermally chemically modified starches obtained from Livingstone potato. Results native starch was by th...
INTRODUCTION Direct compression is the process of tabletting of a blend of ingredients, the compression mix, without a preliminary granulation or aggregation process. The compression mix contains the active pharmaceutical ingredient blended with one or more excipients.1 It has been estimated that less than 20 percent of pharmaceutical materials can be compressed directly into tablets. The rest ...
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