IMPORTANCE Diurnal fluctuations of motor and nonmotor symptoms and a high prevalence of sleep-wake disturbances in Parkinson disease (PD) suggest a role of the circadian system in the modulation of these symptoms. However, surprisingly little is known regarding circadian function in PD and whether circadian dysfunction is involved in the development of sleep-wake disturbances in PD. OBJECTIVE...

Objective sleepiness evaluation is essential for the effect analysis of countermeasures for driver sleepiness, such as in-car stimulants. Furthermore, measuring drivers’ sleepiness in simulator studies also becomes important when investigating causes for task-related sleepiness, for example driving on monotonous routes, which requires little driver engagement. To evaluate driver sleepiness and ...

SLEEPINESS IS A MAJOR CONTRIBUTING FACTOR IN THE FREQUENCY OF HIGHWAY VEHICLE CRASHES and has serious consequences as it leads to a far higher fatality rate than other factors.1,2,3,4 The available data regarding the incidence of sleepiness vary considerably from country to country according to police methods for gathering data, to the population studied, to the definition of sleepiness adopted...

OBSTRUCTIVE SLEEP APNEA (OSA) WITH DAYTIME HYPERSOMNOLENCE IS PRESENT IN AT LEAST 12 MILLION ADULTS IN THE UNITED STATES.1 TWO THIRDS of adults with OSA complain of significant sleepiness and/or fatigue at presentation.2 Yet, therapies may not fully reverse hypersomnolence.3-6 Thus, residual sleepiness in adults treated for OSA is a significant health concern. Adult male mice exposed to hypoxia...

PURPOSE OF REVIEW The majority of the adult population is affected by obstructive sleep apnea (OSA), according to recent epidemiological research. Oral appliance (OA) therapy is increasingly recommended, particularly for patients with milder OSA. This review updates the evidence in favor of OA therapy. RECENT FINDINGS A high level of evidence shows that OA is effective in the treatment of OSA...

Obstructive sleep apnoea is associated with an increased risk of sleep-related motor vehicle accidents. Seven recent legal cases of fatal motor vehicle accidents on NSW roads are presented, where the driver who caused the accident was suffering from an unrecognised or under-treated sleep disorder. The legal outcomes in these cases were variable: some of the drivers have been acquitted and other...

INTRODUCTION Sleepiness in students has an impact on their learning, focus and memory. Sleepiness is caused by multiple factors. Therefore, our objective was to estimate the frequency of sleepiness in Peruvian students and assess its relation to lifestyle and sleep habits. METHODS Cross-sectional study conducted on first through fifth year secondary students. The Spanish version of the pediat...