نتایج جستجو برای: gastric blood flow

تعداد نتایج: 1186640  

2018
Dora Reglodi Anita Illes Balazs Opper Eszter Schafer Andrea Tamas Gabriella Horvath

Pituitary adenylate cyclase activating polypeptide (PACAP) is a multifunctional neuropeptide with widespread occurrence throughout the body including the gastrointestinal system. In the small and large intestine, effects of PACAP on cell proliferation, secretion, motility, gut immunology and blood flow, as well as its importance in bowel inflammatory reactions and cancer development have been s...

2012
Victoria Serelli-Lee Khoon Lin Ling Cassandra Ho Lai Han Yeong Gek Keow Lim Bow Ho Soon Boon Justin Wong

BACKGROUND Ongoing Helicobacter pylori (HP) infection triggers a chronic active gastritis. Eradicating HP reduces gastric inflammation, but does not eliminate it. We sought to characterize this persistent gastritis, and demonstrate the persistence of HP-specific Th17 responses in individuals previously infected with HP but who no longer had evidence of ongoing infection. METHODOLOGY/PRINCIPAL...

Journal: :Biological & pharmaceutical bulletin 2002
Kazunori Hashimoto Yoshio Kase Pin Murata Toshitaka Kido Yoichiro Nakai Iwao Sakakibara Masami Higuchi Hiroshi Sasaki Minoru Okada

Zingiberis Rhizoma (Shokyo, [Japanese characters: see text]) showed significant ameliorative effect on the BaCl2-induced delay of gastric emptying in rat. Bioassay-guided fractionation of the aqueous extract of Shokyo resulted in isolation of 6-gingesulfonic acid (1) and shogasulfonic acid A (3). These compounds significantly improved the delay of gastric emptying on both BaCl2-induced and N(G)...

Journal: :The Journal of pharmacology and experimental therapeutics 2008
Tomasz Brzozowski Peter C Konturek Stefan Chlopicki Zbigniew Sliwowski Michal Pawlik Agata Ptak-Belowska Slawomir Kwiecien Danuta Drozdowicz Robert Pajdo Ewa Slonimska Stanislaw J Konturek Wieslaw W Pawlik

1-Methylnicotinamide (MNA) is one of the major derivatives of nicotinamide, which was recently shown to exhibit antithrombotic and antiinflammatory actions. However, it is not yet known whether MNA affects gastric mucosal defense. The effects of exogenous MNA were studied on gastric secretion and gastric lesions induced in rats by 3.5 h of water immersion and water restraint stress (WRS) or in ...

Journal: :Planta medica international open 2022

Abstract Daikenchuto is a traditional Kampo medicine used to treat cold sensations and dysmotility in the abdomen. This study investigated roles of transient receptor potential ankyrin 1- reporter vanilloid 1-expressing sensory nerves daikenchuto-induced gastric mucosal blood flow by pharmacological immunohistochemical analyses using male Sprague-Dawley rats. Gastric was measured ex vivo stomac...

Journal: :Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2013
A Szlachcic J Majka M Strzalka J Szmyd R Pajdo A Ptak-Belowska S Kwiecien T Brzozowski

Hormonal peptides like ghrelin, orexin A (OXA) or nesfatin-1 not only regulate appetite, which is their basic biological function, but also contribute to mechanisms responsible for maintaining integrity of the gastric mucosa. Previous studies including those from our laboratory have revealed that their gastroprotective effect results from cooperation with other factors responsible for protectio...

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