The hom family of Helicobacter pylori outer-membrane proteins, especially the homB gene, has been suggested as a novel virulence factor; however, the clinical association and function of this gene are still unclear. We evaluated the presence of the homA, homB, and cagA genes in 286 strains isolated from patients in the U.S. and Colombian populations (126 with gastritis, 96 with duodenal ulcer, ...

BACKGROUND Laparoscopic and endoscopic cooperative surgery (LECS) was performed for the local resection of gastrointestinal stromal tumors (GIST). LECS enables less resection of the lesion area and preserves function. Furthermore, LECS can be safely performed and independent of tumor location. However, LECS is not usually used for cases involving gastric carcinoma because it may seed tumor cell...

Current anti-gastric ulcer agents have side effects, despite the progression and expansion of advances in treatment. This study aimed to investigate the gastroprotective mechanisms of Pithecellobium jiringa ethanol extract against ethanol-induced gastric mucosal ulcers in rats. For this purpose, Sprague Dawley rats were randomly divided into five groups: Group 1 (normal control) rats were orall...

Herbal medicines appeared promising in prevention of many diseases. This study was conducted to investigate the gastroprotective effect of Curcuma xanthorrhiza leaf in the rats induced gastric ulcer by ethanol. Normal and ulcer control received carboxymethycellulose (5 mL/kg) orally, positive control was administered with 20 mg/kg omeprazole (reference drug) and 2 groups were received 250 mg/kg...

The present study was performed to evaluate the anti-ulcerogenic activity of hyaluronic acid against ethanol induced gastric mucosal injury in rats. Four groups of adult Sprague Dawley rats were orally pretreated respectively with distilled water (ulcer control groups), omeprazole (reference group), high molecular weight hyaluronic acid and 0.8% hyaluronic acid gel (experimental groups) one hou...

BACKGROUND The mechanisms whereby Helicobacter pylori produces different pathological manifestations in the stomach and duodenum are not fully understood. Considering the geographic diversity in the prevalence of virulence factors of this microorganism and their association with the development of different diseases, the search for pathogenicity markers such as CagA and VacA alleles by molecula...

We studied the relationship between gastroduodenal inflammation and the presence of Campylobaeter pylori from biopsy specimens of the gastric mucosa in 91 patients with gastritis with or without ulcers and 9 controls, healthy or suffering from other diseases. 68 of the patients were positive for the presence of C. pylori in their gastric mucosa. C. pylori was confirmed bacteriohistological...

Cigarette smoking has been linked with duodenal ulcer disease although the mechanism of this association is unclear. This study assessed basal gastric secretory response to acute smoking of smokers with an active duodenal ulcer; in addition the possible effects of chronic smoking on gastric secretory capacity, as expressed by pentagastrin stimulated gastric acid secretion and fasting serum peps...

the aim of the present study was to determination the prevalence of gastric ulcer in caspian miniature horse. the design field- laboratorial study on 23 caspian miniature horses. feed withdraw 12-16 hours before study and the owners or riders completed a form about housing, medication, age, sex, cell boold counts and the biochemical profile tests were carried out. endoscope performed through th...

Background. Scrub typhus results in vasculitis due to Orientia tsutsugamushi infection. The present study investigated whether O. tsutsugamushi infection is associated with gastric ulcer etiology and whether immunohistochemical staining of stomach tissue is useful to diagnose scrub typhus. Methods. A 78-year-old woman was hospitalized owing to general weakness that begun 4 days prior. As scrub ...