OBJECTIVE To determine the prevalence of gastroesophageal reflux disease (GERD) and to evaluate its clinical presentation, as well as the esophageal function profile in patients with idiopathic pulmonary fibrosis (IPF). METHODS In this prospective study, 28 consecutive patients with IPF underwent stationary esophageal manometry, 24-h esophageal pH-metry and pulmonary function tests. All patie...

This article provides an overview of the literature data on problem prevalence gastroesophageal reflux disease. Some pathophysiological aspects this pathology are analyzed. The authors conclude that disease is a common clinical affects millions people around world, according to some reports, up 25–30% adult population affected by it. Patients recognized both classic and atypical symptoms. GERD ...

One of the most common pathologies in structure digestive diseases is gastroesophageal reflux disease (GERD), which associated with low life quality patients, while insufficient control — an increased risk Barrett's esophagus and, as a consequence, adenocarcinoma. In accordance relevant consensus papers, particular, Lyon Consensus, key factor GERD pathogenesis persistent disorder upper tract mo...

BACKGROUND/AIMS Globus is a foreign body sense in the throat without dysphagia, odynophagia, esophageal motility disorders, or gastroesophageal reflux. The etiology is unclear. Previous studies suggested that increased upper esophageal sphincter pressure, gastroesophageal reflux and hypertonicity of esophageal body were possible etiologies. This study was to quantify the upper esophageal sphinc...

RATIONALE The patient had symptoms of GERD and the reflux even caused the symptom of cough. Gaining weight is a risk factor for the treatment of reflux as it could exacerbated symptoms of reflux and the drug treatment is not effective. Surgical intervention becomes necessary when there is failure following conservative medical therapy or the patient. PATIENT CONCERNS The patient was not satis...

OBJECTIVES To evaluate the correlation of gastroesophageal reflux disease (GERD) symptoms with routine post dinner physical activity and time interval before going to bed, in multiethnic South Asian population. METHODS Prospective, cross sectional analytical, multicenter study was conducted from February 2009 to March 2010. Patient's relative sitting in outpatient clinics with no comorbids, n...

INTRODUCTION Ineffective esophageal motility (IEM) is a frequent finding in patients with gastroesophageal reflux disease (GERD). It is responsible for delayed acid clearance as it affects esophageal emptying and saliva transport. Since erosive GERD is a more severe disease than nonerosive GERD, it may be associated with IEM, which delays esophageal clearance. Objective : We investigated the ro...

VV Gastroesophageal reflux disease (GERD) results from the failure of the lower esophageal sphincter to keep acid and other fluids in the stomach. This incompetency is commonly caused by the presence of a hiatal hernia, although a person can have pathologic reflux without a hiatal hernia and, conversely, can have no pathologic reflux even in the presence of a hiatal hernia. Most reflux is actua...

Introduction Laparoscopic antireflux surgery (LARS) has shown excellent results for treatment of gastroesophageal reflux disease (GERD). With success rates between 93% and 97% and a low incidence of complications. Life expectancy in our country is increasing and more patients over 65 years of age are admitted for surgical intervention. The aim of this retrospective study was to compare reflux a...

BACKGROUND Reflux disease is a common gastrointestinal problem. The association between reflux disease and gastritis pattern is controversial. AIM To determine the association between reflux disease and gastritis pattern in patients with Helicobacter pylori (H. pylori) infection. METHODS 470 patients with dyspepsia and reflux disease were enrolled in this study. The inclusion criteria were wi...