Recall appropriate therapeutic recommendations with respect to cardiovascular and gastrointestinal patient risk factors. Educational Objectives strated a reduced risk of gastrointestinal mucosal injury. However, there appears to be a delicate balance between the ability to protect the gastric mucosa and the effect on thrombotic events. Although selective COX-2 inhibitors appear to protect the g...

rntro Cystom. (lntestin;.il Duplications and , or intes-, SUtinal Cysts). These are . congenital cysts who contain  wall has a same histologie pattern as intestinal wall, and they are common in ab- dominal cavity and 70% of them are located in ileocecal region. Twenty percent (20%)oi these cysts have a entrance to intestinal lumen and the rest of them are closed cysts. With duplications in thor...

Irritable bowel syndrome (IBS) is a highly prevalent gastrointestinal disorder characterized by abdominal pain and discomfort in association with altered bowel habits. It is estimated to affect 10%-15% of the Western population, and has a large impact on quality of life and (in)direct healthcare costs. IBS is a multifactorial disorder involving dysregulation within the brain-gut axis, and it is...

INTRODUCTION Acute corrosive poisonings are caused by ingestion of corrosive chemicals which are most commonly used as household agents. Intoxications with these kind of agents produce numerous and severe post-corrosive complications of the upper gastrointestinal tract. On the other hand, our experience showed that corrosive agents may also cause injuries of the respiratory system, which makes ...

Osteoarthritis (OA) is increasingly prevalent worldwide and is associated with a significant economic burden. Despite the increasing number of patients with OA, treatments to manage the condition remain symptomatic, designed to control pain, and improve function and quality of life while limiting adverse events. Both the EULAR (European League Against Rheumatism) and the OARSI (Osteoarthritis R...

The Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder worldwide with unclear etiology. It is considered a chronic, multifactorial, relapsing functional bowel disorder normally related to altered motility of gastrointestinal system and the mechanisms involved in its onset and progression are not clear. The abdominal discomfort or pain and modifications in bowel habit ar...

Nonsteroidal anti-inflammatory drugs (NSAIDs) are highly effective in treating the pain and inflammation associated with osteoarthritis and rheumatoid arthritis, but it is well recognized that these agents are associated with substantial gastrointestinal toxicity. Treatment guidelines suggest that patients with one or more risk factors for NSAID associated ulcers should be prescribed preventive...

OBJECTIVE To assess the general use of all non-steroidal anti-inflammatory drugs (NSAID) and their relation to upper gastrointestinal bleeding in view of National Institute for Clinical Excellence guidelines published in July 2001 in the UK. METHODS Cross sectional study on all patients who were referred for endoscopy for suspected upper gastrointestinal bleeding in six hospitals in Yorkshire...

The recent introduction of immune checkpoint inhibitor therapy with anti- PD-1 agents has shown encouraging responses in gastrointestinal oncology. However, it is also known to possibly result uncontrolled T cell autoreactivity, leading a broad range related adverse events. We present patient who developed sequential immune-related hematologic and hepatic complications following pembrolizumab f...

Although many studies have demonstrated the physiological action of motilin on the migrating motor complex, the precise mechanisms remain obscure. To obtain new insights into the mechanisms, we focused on the house musk shrew (Suncus murinus, suncus used as a laboratory name) as a small model animal for in vivo motilin study, and we studied the physiological characteristics of suncus gastrointe...