oxaliplatin, a third generation of platinum-based anti-neoplastic agent has been approved for colorectal cancer in both adjuvant and metastatic settings. in addition, oxaliplatin is also indicated for other gastrointestinal malignancies such as metastatic pancreatic cancer in combination with gemcitabine. its common toxicities include infusional hypersensitivity reaction (hsr), gi symptoms with...

introduction: accurate diagnosis and proper treatment of oncology patients presented to emergency department (ed) can dramatically enhance their quality of life and decrease their mortality rate. therefore, the present study aimed to evaluate these patients from an epidemiologic point of view as well as identifying death-related factors. methods: in this retrospective cross-sectional study, all...

BACKGROUND Gastrointestinal cancer tumour markers are valuable in the detection of recurrence following resection or in monitoring response to chemotherapy. CEA, CA19-9, CA-50 and CA72-4 are currently available but are nonspecific and have a low sensitivity. 'Tumour M2-pyruvate kinase' was described by Eigenbrodt around 1985. In cancers the active tetrameric form of the M2 isoenzyme of pyruvate...

Gastrointestinal cancers account for 37% of all cancer deaths worldwide, underlining the need to further investigate modifiable factors for gastrointestinal cancer risk and prognosis. This review summarizes the corresponding evidence for physical activity (PA), including, briefly, possible biological mechanisms. Despite high public health relevance, there is still a scarcity of studies, especia...

background: colorectal cancer is one of the most common gastrointestinal cancers accounting for about 10 percent of cancer-related mortalities. the present study was performed in order to investigate the relationship between nutritional factors and colorectal cancer risk in the population of yazd, iran.   methods: this case-control study was conducted on 60 patients with colorectal cancer and 1...

BACKGROUND Programmed cell death 1 ligand 1 (PD-L1) expression has been observed in various malignancies. However, the association between PD-L1 expression and the survival of patients with gastrointestinal tract cancer remains controversial. Besides, the rate of PD-L1 positivity on tumor cells of digestive tract cancer is not clear. Thus, we performed a meta-analysis by incorporating all avail...

Small bowel metastases due to lung cancer are extremely rare and predominantly cause intestinal obstruction, perforation gastrointestinal bleeding. We report the case of a 51-year-old man diagnosed with pulmonary sarcomatoid carcinoma which an ileal mass was subsequently removed found be compatible localization carcinoma.