BackgroundReduced gastrointestinal motility can alter the toxicokinetics of acetaminophen poisoning. We report a case of altered acetaminophen toxicokinetics due to delayed gastrointestinal absorption, likely secondary to intestinal trauma/surgery.  Case ReportA 37-year-old woman ingested an unknown amount of acetaminophen and ethanol then stabbed herself in the abdomen. The initial acetaminoph...

although gastrointestinal involvement by metastatic malignant melanoma is common but primary gastrointestinal (gi) melanoma has been reported in rare cases. in this study we report two cases of primary gastrointestinal malignant melanoma that one of them is a known case of neurofibromatosis type 1(nf1). both cases showed no evidence of any lesions in skin and eye. malignant melanoma of gi tract...

a rare case of diffuse lymphomatous polyposis of the gastrointestinal tract is reported in which the patient presented with abdominal pain, weight loss and bloody diarrhea. x-rays revealed multiple polyps involving the stomach, small intestine and colon. biopsies confirmed the diagnosis of lymphomatous polyposis. the duration of symptoms and signs was 3 months. diffuse lymphomatous polyposis of...

common variable immunodeficiency (cvid) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. we present here 2 cases of cvid with gastrointestinal complications. case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. ultrasonography revealed ascites, with l...

Objective: To investigate the epidemiology and spectrum of upper gastrointestinal (UGI) tract injuries, as well to assess burden Corrosive intake patients who presented an Islamabad tertiary care hospital.Study Design: Descriptive cross-sectional.Place Duration Study: The study was carried out at Department Gastroenterology Pakistan Institute Medical Sciences, Islamabad, from January 2021 Decem...

The risk of effects to fishes and other aquatic life from impulsive sound produced by activities such as pile driving and seismic exploration is increasing throughout the world, particularly with the increased exploitation of oceans for energy production. At the same time, there are few data that provide insight into the effects of these sounds on fishes. The goal of this study was to provide q...

The current study was designed to examine the predictive validity of several factors that are common to spinal cord injury (SCI) and traumatic brain injury (TBI) populations to overall life satisfaction. We examined several demographic and functional predictors (1) within each group separately and (2) using both groups while controlling for unique predictors within groups. Participants included...

Partial middle turbinate avulsion is a rare complication of nasotracheal intubation. Patients usually experience a brisk hemorrhage at the time of injury. Postoperatively, some patients develop a unilateral nasal obstruction, while others are asymptomatic. We present an unusual case in which a patient became symptomatic many years after the incident. We hope to raise awareness that a traumatic ...

M1 reported in 1970 that 193 of a cohort of 2,600 casualties that were killed in action in Vietnam died of isolated extremity hemorrhage. The percentage of fatalities that resulted from exsanguination from extremity wounds was 7.9%; this was the leading cause of preventable death among US military casualties in the Vietnam War. Maughon commented at the time that little progress had been made in...