BACKGROUND In high income countries, cancer is one of the leading causes of death, with co-morbid depression contributing to the risk of increased mortality. However, both cancer and depression are neglected conditions in low income countries. The current study assessed the magnitude of depression and the association of pain complaints with depression among patients with cancer in a low income ...

OBJECTIVE The effects of olanzapine and divalproex for the treatment of mania were compared in a large randomized clinical trial. METHOD A 3-week, randomized, double-blind trial compared flexibly dosed olanzapine (5-20 mg/day) to divalproex (500-2500 mg/day in divided doses) for the treatment of patients hospitalized for acute bipolar manic or mixed episodes. The Young Mania Rating Scale and ...

Objective This research developed a practical, multi-dimensional attention deficit hyperactivity disorder (ADHD) rating scale (i.e., the Symptoms and Functional Impairment Rating Scale, SFIRS) for Chinese children, aged 6-12 years, with ADHD. Methods The structural validity, criterion validity, internal consistency, and test-retest reliability of the scale were evaluated. Item screening was c...

PURPOSE To investigate whether pathophysiological differences exist among healthy controls (HC) and patients with slow and normal transit constipation (STC and NTC), we evaluated (1) gastrointestinal (GI) symptoms using validated questionnaires; (2) circulating concentrations of neurotensin, motilin, corticotrophin-releasing factor (CRF), and somatostatin; and (3) possible differences in freque...

OBJECTIVE To prospectively evaluate depressive symptoms and risk factors for depression in patients with chronic hepatitis C (CHC) treated with pegylated interferon alpha therapy combined with oral ribavirin (PEG-IFN-α+RBV) and to analyze self-rating scale for depression in comparison to observer-based scale in the given population. SUBJECTS AND METHODS The Hamilton Depression Rating Scale an...

OBJECTIVE This study analyzed the symptom frequencies of 17-item Hamilton Depression Rating Scale (HDRS-17) to understand the characteristics of each item and to propose the possible symptoms clusters. METHODS From psychiatric clinics of 18 Hospitals in Korea, 1,183 patients, diagnosed with major depressive disorder (psychotic or non-psychotic), dysthymia or depressive disorder not otherwise ...

background: irritable bowel syndrome (ibs) is one of the most common functional gastrointestinal disorders. a signi_cant number of ibs patients have extra-intestinal symptoms (eis), but the etiology of co-morbidity of ibs with these symptoms is unclear. the aim of this study was to evaluate the relationship of eis with psychological symptoms in ibs patients. â  materials and methods: this multi...

impact of psychoeducational groups for caregivers on the psychiatric symptoms of patients with schizophrenia     shaygan m [1] *, sharif f [2]     received: 21 nov, 2012 accepted: 11 feb , 2013     abstract:   background & aims : schizophrenia is a severe psychiatric disorder, which is extremely stressful not only for the persons affected but also for their families.   materials & methods : to ...

BACKGROUND Self-report instruments for the assessment of depressive symptoms in patients with psychotic disorders are scarce. The Quick Inventory of Depressive Symptoms (QIDS-SR16) may be a useful self-report instrument, but has received little attention in this field. This paper aimed to test the psychometric properties of the QIDS-SR16 questionnaire in patients with a psychotic disorder. ME...