BACKGROUND Cancer is the second leading cause of death in the United States. Dietary factors account for at least 30% of all cancers in Western countries. As people do not consume individual foods but rather combinations of them, the assessment of dietary patterns may offer valuable information when determining associations between diet and cancer risk. METHODS We examined the association bet...

The classic concept of gastrointestinal endocrinology is that of a few peptides released to the circulation from endocrine cells, which are interspersed among other mucosal cells in the upper gastrointestinal tract. Today more than 30 peptide hormone genes are known to be expressed throughout the digestive tract, which makes the gut the largest endocrine organ in the body. Moreover, development...

Chlamydia has been detected in the gastrointestinal tracts of both animals and humans. However, the mechanism by which Chlamydia colonizes the gut remains unclear. Chlamydia muridarum is known to spread from the genital to the gastrointestinal tracts hematogenously. The C. muridarum plasmid is a key pathogenic determinant in the mouse upper genital tract although plasmid-deficient C. muridarum ...

BACKGROUND Little is known about the genetic alterations in multiple primary cancers of the gastrointestinal tract. Microsatellite instability (MSI) is frequently observed in hereditary non-polyposis colorectal cancer (HNPCC), and multiple primary cancers is a feature of this syndrome. AIMS To identify MSI incidence, target gene mutation, and mismatch repair (MMR) protein status in patients w...

PURPOSE The maintenance of regional alliance clinical pathways for five cancers (lung, stomach, liver, large intestine, and breast) has been requested along with a readjustment of specific requirements for a plan to promote cancer control measures based on the Cancer Control Act. The aim of this study was to clarify the usefulness of regional alliance clinical pathways for cancer of the gastroi...

The mean relative proportions of a number of blood serum protein fractions assessed electrophoretically are altered in active cancer. The changes in number and degree are generally greater than in other diseases; this may be a reflection of the seriousness of the condition and the extent of tissue involvement. A relative lowering of the proportion of albumin and an increase in that of the vario...