Landfills in the United States are a significant source of pollution to ground and surface water. Current environmental regulations require detection and/or monitoring assessments landfill leachate for contaminants that have been deemed particularly harmful. However, lists be monitored not comprehensive. Further, composition varies over space time, thus contaminants, their corresponding toxicit...

the toxicity of 7 herbicides to the three cyanobacteria was tested in this work. the results indicated that: (1) there was a highly significant relationship between dried weight or chlorophyll-a and od680nm for tested cyanobacteria; (2) the toxicity of the tested herbicides with the order from high to low was: photosynthesis-inhibiting > accase inhibitor > protox inhibiting herbicides; (3) the ...

objectives: nigella sativa (n. sativa) is an amazing herb which is used in traditional medicine for a wide range of illnesses including bronchial asthma, dysentery, gastrointestinal problems, as well as beneficial effect on blood lipids, lowering blood pressure, serum cholesterol, and triglycerides level. this study aimed to determine the toxic effect of n. sativa powder on the kidney function ...

objective: in this study we investigated the effects of spearmint (mentha spicata labiatae) on the reproductive system, fertility and number of offspring in adult male rats. materials and methods: adult wistar male rats in one control (c) and three experimental groups (i, ii and iii) received 0, 10, 20 and 40 mg/kg spearmint extract orally for 45 days, respectively.  following this treatment, t...

silicon is the element very similar to carbon, and bioactive siliconized compounds have therefore received much attention. siliconization of a compound enhances its biological activities. in the present study the hypolipidemic effect and toxicity of clofibrate and its siliconized analog, silafibrate, were compared. the experiments were performed in hypercholesterolemicwistar rats. animals recei...

diphenhydramine, as an antihistamine drug is widely used for the treatment of allergies. however, being classified as an over the counter medication and the general belief on the low adverse effect profile of this drug has made it widely accessible to the families. recent reports of diphenhydramine intoxication and mortality, noticeably in children and infants have raised some serious concerns....

Recent decades have seen a strong increase in the promise and uses of nanotechnology. This is correlated with their growing release in the environment and there is concern that nanomaterials may endanger ecosystems. Silver nanoparticles (AgNPs) have some of the most varied applications, making their release into the environment unavoidable. In order to assess their potential toxicity in aquatic...

Cd 2+ a heavy metal accumulates in the body and has a very long biological half-life (10–30 years) in humans. Environmental cadmium contamination occurs through industries related to batteries, coatings, electroplating, alloys, plastics, glasses, ceramics, enamels and artists’ colors, zinc, copper, lead, and iron ores treatment, coal and oil burning power plants, weathering of parent rocks etc....

In this study, 602 samples were tested by the following assays performed at the animal facilities (Cedeme) of the Federal University of São Paulo (UNIFESP): 385 for dermal irritability, 90 for ocular irritability (discontinued in 1995), 31 for systemic toxicity by injection, 26 for oral acute toxicity, 15 for toxicity by intracutaneous injection, 15 for skin sensitization, 15 for toxicity of se...

A survey conducted on the EU Notification of New Substances (NONS) database suggested that for industrial chemicals with a profile of low toxicity in (sub)acute toxicity tests there is little added value to the conduct of the 90-day repeated dose study. Avoiding unnecessary animal testing is a central aim of the EU REACH chemicals legislation; therefore we sought to verify the profile using add...