Abstract In this work we aim to empirically characterize two important dynamical aspects of GP search: the evolution diversity and propagation inheritance patterns. Diversity is calculated at genotypic phenotypic levels using efficient similarity metrics. Inheritance information obtained via a full genealogical record as directed acyclic graph set methods for extracting relevant Advances in pro...

Background Brown−Vialetto−Van Laere syndrome (BVVLS) and Fazio−Londe disease (FLD) are rare neurological disorders presenting with pontobulbar palsy, muscle weakness respiratory insufficiency. Mutations in SLC52A2 (hRFVT-2) or SLC52A3 (hRFVT-3) genes can be responsible for these an autosomal recessive pattern of inheritance. The aim this study was to screen mutations among Indian families diagn...