Background. Continuous Training (CT) is often considered an effective way to reduce obesity. However, recently, a popular protocol called High-Intensity Interval Training (HIIT) has shown up as an alternative to CT. There is another factor affecting obesity named UCP2 45-bp Insersion/Deletion genetic marker. Objectives. This research aims to determine the effect of the UCP2 45-bp I/D gene as a...

Objective: Evidence suggests the increased prevalence of diabetes among South Asian (SA) adolescents is due to their genetic risk profile. The Adolescent Diabetes Awareness Program (SAADAP) a pilot intervention for SA youth in Canada with family history type 2 mellitus (T2DM). We sought investigate changes (1) knowledge and associated factors, (2) perception (3) health behaviours participating ...

This article tries to analyze the interaction between the implementation of a microfinance project in a rural area and the social and cultural infrastructure prevailing in the project site. In 2000, 53 women in a small village in central Iran formed an association of beekeepers with the support of a developmental intervention promoting microfinance as a strategy for poverty alleviation. Because...

Heterogeneity in attention-deficit/hyperactivity disorder (ADHD), with complex interactive operations of genetic and environmental factors, is expressed in a variety of disorder manifestations: severity, co-morbidities of symptoms, and the effects of genes on phenotypes. Neurodevelopmental influences of genomic imprinting have set the stage for the structural-physiological variations that modul...

BACKGROUND We assessed whether 234 established dyslipidemia-associated loci modify the effects of metformin treatment and lifestyle intervention (versus placebo control) on lipid and lipid subfraction levels in the Diabetes Prevention Program randomized controlled trial. METHODS AND RESULTS We tested gene treatment interactions in relation to baseline-adjusted follow-up blood lipid concentrat...

There is robust evidence that the interparental relationship and parenting behaviors each have a significant influence on children's risk for emotional (internalizing) and behavioral (externalizing) problems. Indeed, interventions targeting the interparental relationship and parenting processes show significant intervention-related reductions in child internalizing and externalizing problems. H...

The amygdala is critically involved in detecting emotionally salient stimuli and in enhancing memory for emotional information. Growing evidence also suggests that the amygdala plays a crucial role in addiction, perhaps by strengthening associations between emotionally-charged drug cues and drug-seeking behavior. In the current study, by integrating functional MRI (fMRI), genetics, and outcome ...

This research reviews the current state of affairs in the fast-growing area of direct-to-consumer marketing of genetic tests. The authors identify the unique nature of genetic tests and the ensuing consumer vulnerability. They also present a comprehensive examination of the current legal environment and an empirical analysis of genetic testing companies’ online marketing practices. On the basis...

Letter written by boy aged 11 with Duchenne muscular dystrophy. The prevention of inherited disease by means of genetic and reproductive counselling and prenatal diagnosis is often emphasised. Genetic disorders may, however, be amenable to treatment, either symptomatic or potentially curative. Treatment may range from conventional drug or dietary management and surgery to the future possibility...