About three in 10 men and women taking part in a prospective longitudinal study in rural Uganda reported having had genital ulcers, according to data from more than 500 participants.1 Those infected with HIV were substantially more likely than other individuals to have had genital ulcers; in the subgroup with HIV infection, men were significantly more likely than women to report the condition. ...

OBJECTIVES This paper reports on the cross sectional data from the longitudinal study examining the impact of genital herpes simplex virus (HSV) infection on quality of life. In particular the report sought to study the relation between recurrence of genital HSV and coping style, mood, personality, and quality of life, among other factors. SETTING AND SUBJECTS 116 patients with a known histor...

Herpes simplex virus (HSV) and varicella-zoster virus (VZV) are both human alpha-herpes viruses. They are capable of establishing latent infections in neural tissues and to reactive from these sites, determining the clinical features of the disease (primary infection versus recurrences). Infections with these viruses are common; an increased number of elderly and immunocompromised individuals w...