Sir, Imiquimod, a non-nucleoside heterocyclic amine, is a member of a new class of immune response-modifying agents (1). Topical use of imiquimod as an immune system modi® er for the treatment of genital and perianal warts has recently been described (2, 3). However, the utility of this agent for the treatment of warts located on other areas of the skin is unknown. We describe here a patient wi...

Human papilloma virus (HPV) infection is one of the most common sexually transmitted infections in the world. In genitalia, it causes a broad spectrum of lesions, from wart to intraepithelial neoplasia and carcinoma. The objective of this descriptive study was the distribution of the infection in our region based on gender, age, marital status and high risk sexual behaviors. Eighty one patients...

OBJECTIVE To evaluate the efficacy-safety ratio of a new topical podophyllotoxin cream 0.5% compared with podophyllotoxin solution 0.5% (Condyline) in male patients with genital warts. METHODS In an observer-blinded controlled study a total of 136 and 133 wart lesions were treated with podophyllotoxin cream 0.5% and podophyllotoxin solution 0.5%, respectively. The preparations were applied tw...

OBJECTIVE To compare anal cytology, colposcopy and DNA hybridisation as methods of detecting anal HPV infection. SUBJECTS AND DESIGN Patients attending: (1) a genitourinary medicine (GUM) clinic with ano-genital warts; (2) a surgical out-patient department with anal fissure or haemorrhoids were examined for evidence of anal HPV infection. RESULTS Considering GUM clinic attenders, 17% (38/22...