Questionnaire based assessment scales for gastroesophageal reflux disease (GERD) have been utilized for assessment of the patient's symptomatology, assessment of symptom severity and frequency, assessment of health-related quality of life and for assessment of response to treatment. A multitude of unidimensional and multidimensional questionnaires exist for making symptom assessment and monitor...

Multiple new endoluminal devices and therapies have been devised to create a more effective antireflux barrier in patients with gastroesophageal reflux disease (GERD). Most of these therapies have been abandoned, because they were ineffective and/or had significant adverse effects. However, there are currently two therapies (Stretta, EsophyX) that have US Food and Drug Administration approval a...

background: gastroesophageal reflux disease (gerd) is one of the most common gastrointestinal problems in the west while different reports indicate an increase in the prevalence in iran. the aim of this study was to estimate the preva­lence and clinical spectrum of gerd in staff of a referral hospital and evaluate the risk factors. methods: this cross-sectional study using a modified mayo clini...

Gastroesophageal reflux (GER) is a common problem in infants and children. Physiologic vomiting is common in the first 6 months to 1 year of life. However, pathologic gastroesophageal reflux disease (GERD) can present in childhood. Pathologic GERD is the occurrence of reflux with associated complications that can include failure to thrive, aspiration, laryngospasm, and esophagitis.1 Treatment o...

Gastroesophageal reflux (GER), represents the retrograde movement of gastric contents into the esophagus, and is a frequently experienced benign but symptomatic condition. At the one end of the spectrum are infants with physiologic reflux, also referred to in the United States as “happy spitters”, and at the other end are children with objective pathologic sequelae comprising gastroesophageal r...

Gastroesophageal reflux disease (GERD) is widely associated with asthma, chronic cough, and laryngitis. Many studies have focused on acidic reflux; however, acid is just one of many factors that can cause pulmonary injury. The discrepancy between the high frequency of GERD in asthmatic patients and the ineffective reflux therapy outcomes in these patients suggests that GERD may cause injury thr...

The relationship between hiatal hernias and gastroesophageal reflux disease (GERD) has been greatly debated over the past decades, with the importance of hiatal hernias first being overemphasized and then later being nearly neglected. It is now understood that both the anatomical (hiatal hernia) and the physiological (lower esophageal sphincter) features of the gastroesophageal junction play im...

BACKGROUND/AIMS Patients with type II diabetes mellitus (DM) were known to have higher prevalence of gastroesophageal reflux disease (GERD). Recent studies have shown that neuropathy has positive role on the development of GERD in type II DM, although its pathogenesis has not been fully understood yet. The aim of this study was to investigate whether neuropathy really contribute to the developm...

BACKGROUND Bariatric surgery is the most effective treatment for gastro-esophageal reflux disease (GERD) in obese patients, with the Roux-en-Y gastric bypass being the technique preferred by many surgeons. Published data reporting the results of laparoscopic sleeve gastrectomy (LSG) in patients with GERD are contradictory. In a previous observational study, we found that relative narrowing of t...

Gastroesophageal reflux disease (GERD) occurs when acid or other stomach contents back up in the esophagus. The most common symptom of GERD is heartburn, which, while rarely life-threatening, can greatly reduce a patient’s quality of life by affecting daily activities, sleep and what they can eat [1,2]. A systematic review found the prevalence of GERD to be 1020% of the Western world with a low...