نتایج جستجو برای: gi disease

تعداد نتایج: 1504066  

2016
Laura Chiavaroli Arash Mirrahimi Christopher Ireland Sandra Mitchell Sandhya Sahye-Pudaruth Judy Coveney Omodele Olowoyeye Tishan Maraj Darshna Patel Russell J de Souza Livia S A Augustin Balachandran Bashyam Sonia Blanco Mejia Stephanie K Nishi Lawrence A Leiter Robert G Josse Gail McKeown-Eyssen Alan R Moody Alan R Berger Cyril W C Kendall John L Sievenpiper David J A Jenkins

INTRODUCTION Type 2 diabetes (T2DM) produces macrovascular and microvascular damage, significantly increasing the risk of cardiovascular disease (CVD), renal failure and blindness. As rates of T2DM rise, the need for effective dietary and other lifestyle changes to improve diabetes management become more urgent. Low-glycaemic index (GI) diets may improve glycaemic control in diabetes in the sho...

2012
Christina Bannert Bettina Bidmon-Fliegenschnee Georg Stary Florian Hotzy Judith Stift Samuel Nurko Zsolt Szépfalusi Edda Fiebiger Eleonora Dehlink

BACKGROUND The role of the high affinity IgE receptor, FcεRI, in IgE-mediated immune responses of the gastrointestinal (GI) mucosa is poorly understood. Currently, a detailed characterization of FcεRI expression throughout the human gut is lacking. The aim of this study was to define the expression pattern of FcεRI in the GI tract. METHODS/PRINCIPAL FINDINGS We compared FcεRI expression in ch...

2017
Yuhai Zhao Vivian Jaber Walter J. Lukiw

Although the potential contribution of the human gastrointestinal (GI) tract microbiome to human health, aging, and disease is becoming increasingly acknowledged, the molecular mechanics and signaling pathways of just how this is accomplished is not well-understood. Major bacterial species of the GI tract, such as the abundant Gram-negative bacilli Bacteroides fragilis (B. fragilis) and Escheri...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2013
S Mocellin D Nitti

BACKGROUND Owing to its rarity, the published evidence on gastrointestinal (GI) carcinoid is often based on small series of patients or population-based studies regarding all neuroendocrine tumors. Here, we present a comprehensive epidemiological and survival analysis of the largest cohort of patients with GI carcinoid ever reported. PATIENTS AND METHODS Patients with histological diagnosis o...

Journal: :Journal of clinical pathology 2004
J Krugmann A Tzankov S Dirnhofer F Fend R Greil R Siebert M Erdel

BACKGROUND The most frequent cytogenetic alteration in gastrointestinal (GI) B cell lymphoma (BCL) is t(11;18)(q21;q21). GI B cell non-Hodgkin lymphomas lacking this translocation vary in their biology and clinical outcome. The t(11;18) negative subgroup shows increased numerical changes of chromosome 18, although its clinical relevance remains unknown. METHODS Thirty surgically resected prim...

2010
S Paydar SR Baezzat A Fazelzadeh B Geramizadeh

Zygomycosis is regarded as a rare fetal infection in diabetics and other immunocompromised patients. The usual manifestations of this infection are: rhinosinusitis, pansinusitis, rhino-orbital and rhinocerebral. Primary gastrointestinal (GI) zygomycosis is a rare disease with a high mortality rate. The stomach is the most common site involved in GI mucormycosis. There are few reported cases of ...

2016
Drew Arthur Emge Juri Bassuner Daniel J. Lewis Madeleine Duvic

Extracutaneous involvement in mycosis fungoides (MF) carries a poor prognosis. Oral and gastrointestinal (GI) tract lesions are both rare locations of disease. We describe the clinical findings of one case with oral and GI MF complicated by perforation after systemic antineoplastic treatment, and review the relevant literature. The patient had a 1-year history of MF before development of tongue...

Journal: :Molecular medicine 2008
Inna L Botchkina David E Rivadeneira Kevin Watkins Martin S Karpeh Galina I Botchkina

Early detection and accurate staging of gastrointestinal (GI) cancers are difficult. The aim of this study was to evaluate whether telomerase activity (TA) in exfoliated/disseminated epithelial cells could be used as a reliable marker for GI cancers. TA was evaluated with the real-time RTQ-TRAP in immunomagnetically sorted peritoneal epithelial cells from 60 patients undergoing surgical treatme...

Journal: :Canadian journal of public health = Revue canadienne de sante publique 2008
Manon D Fleury Julie Stratton Carol Tinga Dominique F Charron Jeff Aramini

BACKGROUND Gastrointestinal illness (GI) remains a leading cause of morbidity and mortality worldwide. In Canada, research has already demonstrated a rate in excess of one episode per person-year. National passive surveillance programs may be enhanced by information from hospitalizations for acute gastrointestinal disease. The objective of this report is to explore the incidence of acute GI in ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس 1389

تحریک الکتریکی با فرکانس پایین (lfs) دارای اثرات ضد تشنجی است. یکی از مکانیسم های عمل lfs از طریق فعالیت نوروترانسمیتر هایی است که به پروتیین هایg به خصوص به gi جفت می شوند. بنابراین در این تحقیق تاثیر مهارگر آنزیم فسفودی استراز و نیز تغییر میزان بیان پروتیین gi و gs و پروتیین های تنظیم کننده آن ها، پروتیین های (rgs4، rgs10 و rgs2) به دنبال ایجاد اثرات ضد تشنجیlfs مورد بررسی قرار گرفت. حیوانات ...

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