Pyogenic granuloma, also known as lobular capillary hemangioma, is a common benign vascular proliferative lesion that can present at any age on the skin or mucous membranes. Most lesions do not exceed 2 cm, but there are a handful of giant cutaneous pyogenic granulomas that have been reported, often in individuals with underlying immune dysfunction. Here, we report the first giant pyogenic gran...

Cherubism is a rare bone dysplasia in children characterized by symmetrical resorption limited only to the jaws and diagnosed as lesions filled with soft fibrous giant cell-rich tissue that can expand cause severe facial deformity. Most patients have germline mutations gene encoding SH3BP2, signaling adaptor protein involved adaptive innate immune responses. Treatment depends on clinical course...

Calcifying odontogenic cyst (COC), Central odontogenic fibroma (COF) and aggressive central giant cell granuloma (CGCG) are rare pathologic diseases affecting the jaws. While the Co-existence of two of them is reported in the literature, existence of all three conditions in one patient is an extremely rare entity. In the present report, initial biopsy revealed fibrosarcoma, therefore mandibular...