Endothlin-1 (ET-1) is a 21 amino acid peptide and is a potent vasoconstrictor produced by endothelial cells. It plays a role in the development of diseases such as hypertension and atherosclerosis. Reports have suggested the identification of ET-1 in chronic periodontitis and gingival overgrowth. Thus, there is a need to appraise the role of ET-1 in periodontal disease. Further research is need...

background and aim . gingival recession as the apical migration of the gingival margin that results in exposure of the cementoenamel junction (cej) and the root surface. in this case series we aimed to demonstrate a combination technique using semilunar coronally positioned flap with free gingival graft for root coverage. materials and methods . a total of 12 healthy subjects, 25-45 years of ag...

Background: Saliva despite being rich in ions, proteins, and antibodies also contains antioxidants: ascorbic acid, uric albumin, enzymes, which play an important role against oxidative stresses (OS) that causes oral cavity diseases like periodontitis. The aim of study is to analyze compare the total antioxidant capacity saliva between chronic periodontitis patients (at baseline after therapy) h...

Gingival hyperplasia is a rare condition but it is important for cosmetic and mechanic reasons and because of its potential as an indicator of systemic disease. Gingival fibromatosis may exist as an isolated abnormality or as part of a syndrome. In this article a case that was diagnosed clinically and histologically as idiopathic gingival fibromatosis is presented. Patient with gingival hyperpl...

Pathogenic bacteria constitute the primary extrinsic agent in the etiology of early onset periodontitis. However, the risk of developing periodontal disease is not equal for all individuals, suggesting host factors are involved in determining an individual's disease susceptibility. In this report, a case of an otherwise healthy female, who exhibited prepubertal periodontitis (PPP) at age 10, ju...

AIM To evaluate the prevalence of various gingival biotypes and to corroborate gingival thickness and gingival biotypes across tooth type, site, and gender. MATERIALS AND METHODS A cross-sectional study was conducted across systemically healthy subjects. A systematic clinical evaluation for gingival biotypes and gingival thicknesses was recorded by modified Iwanson's gauge, to the nearest 0.1...

BACKGROUND AND OBJECTIVE Collagen type I elevation in cyclosporin A-induced gingival overgrowth supports evidence that gingival fibroblasts play a decisive role in the manifestation of the phenotype. To analyze the role of gingival fibroblasts under more in vivo-like conditions, we evaluated the effect of cyclosporin A on collagen type I gene and protein expression in gingival overgrowth-derive...

Many terms have been used to describe gingival overgrowth. The expression gingival hyperplasia (“abnormal increase in the number of normal cells in a normal arrangement in an organ or tissue, which increase in volume”) and gingival hypertrophy (“enlargement or overgrowth of an organ or part due to an increase in size of its constituent cells”) have been also used, although gingival overgrowth i...

The gingival recession was evaluated in 400 subjects aged more than 20 years, looking for dental treatment at Rural Dental College and Hospital, Loni, Maharashtra, India. Clinical examination was conducted by a single examiner and analysis of four surfaces (mesial, buccal, distal and lingual) was done. The gingival recession was measured in millimeters from the cementoenamel junction to the gin...