Aircraft landings can be dangerous near airport runways due to wind variability. As a result, an aircraft could potentially miss approach or divert off its flight path. In this study, turbulence intensity along the runway glide path was investigated using scaled-down model of Hong Kong International Airport (HKIA) and complex terrain nearby built in TJ-3 atmospheric boundary layer tunnel. Diffe...

We have estimated affinities for the binding of 34 ligands to trypsin and nine guest molecules to three different hosts in the SAMPL3 blind challenge, using the MM/PBSA, MM/GBSA, LIE, continuum LIE, and Glide score methods. For the trypsin challenge, none of the methods were able to accurately predict the experimental results. For the MM/GB(PB)SA and LIE methods, the rankings were essentially r...

Performance of Glide was evaluated in a sequential multiple ligand docking paradigm predicting the binding modes of 129 protein-ligand complexes crystallized with clusters of 2-6 cooperative ligands. Three sampling protocols (single precision-SP, extra precision-XP, and SP without scaling ligand atom radii-SP hard) combined with three different scoring functions (GlideScore, Emodel and Glide En...

PURPOSE The aim of this study was to analyse changes taking place within selected kinematic parameters of the swimming start, after completing a six-week plyometric training, assuming that the take-off power training improves its effectiveness. METHODS The experiment included nine male swimmers. In the pre-test the swimmers performed three starts focusing on the best performance. Next, a plyo...

BACKGROUND In a structure-based virtual screening, the choice of the docking program is essential for the success of a hit identification. Benchmarks are meant to help in guiding this choice, especially when undertaken on a large variety of protein targets. Here, the performance of four popular virtual screening programs, Gold, Glide, Surflex and FlexX, is compared using the Directory of Useful...

An interesting characteristic of avian gliders is their ability to soar or remain aloft without flapping their wings for long periods. There are two ways to do this. In static soaring a bird maintains or gains altitude by gliding in air that has an upward velocity component equal to or greater than the bird's sinking speed. In dynamic soaring a bird uses changes in the horizontal wind-velocity ...

Aimed at joint state and parameter estimation problems in hypersonic glide vehicle defense, a novel moving horizon algorithm via Carleman linearization is developed this paper. First, the maneuver characteristic parameters that reflect target law are extended into vector, dynamic tracking model applicable to various vehicles constructed. To improve accuracy, constraints such as path change ampl...