نتایج جستجو برای: glucose transporter type 4

تعداد نتایج: 2609401  

Journal: :Indonesian Journal of Biotechnology 2022

Andrographolide has been shown to have a pharmacological effect as an antidiabetic. Nevertheless, the comprehensive mechanism of action yet be determined. is primary component sambiloto herb (Andrographis paniculata (Burm.f.) Nees), in which simple isolation process can obtain high yields. This study aimed explain anti‐diabetic andrographolide compared pioglitazone (a positive control) on gluco...

Journal: :American journal of physiology. Heart and circulatory physiology 2017
Edith Renguet Audrey Ginion Roselle Gélinas Laurent Bultot Julien Auquier Isabelle Robillard Frayne Caroline Daneault Jean-Louis Vanoverschelde Christine Des Rosiers Louis Hue Sandrine Horman Christophe Beauloye Luc Bertrand

High plasma leucine levels strongly correlate with type 2 diabetes. Studies of muscle cells have suggested that leucine alters the insulin response for glucose transport by activating an insulin-negative feedback loop driven by the mammalian target of rapamycin/p70 ribosomal S6 kinase (mTOR/p70S6K) pathway. Here, we examined the molecular mechanism involved in leucine's action on cardiac glucos...

Journal: :The Journal of biological chemistry 1993
L Xia Z Lu T C Lo

The present investigation examined the glucose transporter (GLUT) transcript levels in glucose-grown rat L6 myoblasts, which possessed a high (HAHT) and a low (LAHT) affinity hexose transport system. The most prominent GLUT transcript detected in these cells was a GLUT 3-recognizable 4.1-kilobase transcript. Mutants defective in HAHT contained only residual levels of the GLUT 3 transcript and t...

Journal: :iranian journal of basic medical sciences 0
seyyedeh raheleh hosseyni-talei immunogenetic research center, mazandaran university of medical sciences, sari, iran abdolkarim mahrooz immunogenetic research center, mazandaran university of medical sciences, sari, iran department of clinical biochemistry and genetics, faculty of medicine, mazandaran university of medical sciences, sari, iran mohammad bagher hashemi-soteh immunogenetic research center, mazandaran university of medical sciences, sari, iran maryam ghaffari-cherati immunogenetic research center, mazandaran university of medical sciences, sari, iran ahad alizadeh department of epidemiology and reproductive health, reproductive epidemiology research center, royan institute for reproductive biomedicine, acecr, tehran, iran

objective(s): organic cation transporter 3 (oct3) as a high-capacity transporter contribute to the metabolism of metformin. the present study was conducted to determine the genotype frequencies of the variant oct3-1233g>a (rs2292334) in patients with newly diagnosed type 2 diabetes (t2d) and its relationship with response to metformin. materials and methods: this study included 150 patients wit...

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