of stones from the gall bladder.3 There are several clinical implications. The long contiguous course of the cystic duct and common hepatic duct could explain why surgeons sometimes inadvertently leave a long remnant of cystic duct, which is reputedly a cause of the postcholecystectomy syndrome.4 Furthermore, the migration of stones from the gall bladder into the contiguous segment may explain ...

Felodipine is a long-acting 1, 4-dihydropyridine calcium channel blocker, used to control hypertension by selective action on peripheral resistance. The conventional felodipine tablet gives a rather high peak and comparatively low trough levels, due to rapid absorption and distribution. More sustained plasma concentrations might thus produce a more even effect on blood pressure. The main aim of...

The relative efficacy of two calcium antagonist drugs, verapamil, 120 mg three times a day and nifedipine, 20 mg three times a day, was examined in a double-blind randomised trial. Patients were assessed at the end of four week periods by a maximal treadmill exercise test, the frequency of anginal attacks, glyceryl trinitrate consumption, and side effects. Sixteen point praecordial maps were re...

The stereochemistry of the hydrolysis of radioactive glyceryl trioleate and glyceryl diether-monoesters by lipase activity in post-heparin plasma from man, normal and hepatectomized rats, and rat liver perfusate was determined. The following substrates were chemically synthesized and employed in albumin-Triton X-100 emulsions: 1,2 dioleoyl-3 [9,10 3H]oleoyl sn glycerol; 1,3 dioleoyl2 [l W]oleoy...

BACKGROUND The present paper describes the isolation and characterization of two new aliphatic δ-lactones along with three glycerides and n-nonadecanyl cetoleate from the fruits of Coriandrum sativum L. (Apiaceae). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions. RESULTS Phytochemical investigation of the...

In order to obtain information on the mechanism of ether bond formation in the synthesis of 0-alkyl lipids, a study was carried out to determine if there is a loss of hydrogen from carbon 3 of dihydroxyacetone phosphate (DHAP) (nonphosphorus-linked carbon) in the course of its incorporation into glyceryl ethers. Accordingly, a mixture of [1,3-3H2] DHAP and [I ,3-WJDHAP was prepared. In a micros...