Treatment of isogenic suspension-cultured cells of Nicotiana silvestris Speg. et Comes with glyphosate (N-[phosphonomethyl]glycine) led to elevated levels of intracellular shikimate (364-fold increase by 1.0 millimolar glyphosate). In the presence of glyphosate, it is likely that most molecules of shikimate originate from the action of 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAHP) synthase...

The toxicity of the active molecule in herbicides has been used to determine safe concentrations, because other components are considered inert. Roundup, which contains the active molecule Glyphosate, was described as an endocrine disrupter because non-cytotoxic concentrations inhibited progesterone synthesis in vitro. Human chorioplacental JAr cells synthesise progesterone, and increase synthe...

Glyphosate [N-(phosphonomethyl) glycine]-resistant crops (GRCs), canola (Brassica napus L.), cotton (Gossypium hirsutum L.), maize (Zea mays L.), and soybean [Glycine max (L.) Merr.] have been commercialized and grown extensively in the Western Hemisphere and, to a lesser extent, elsewhere. Glyphosate-resistant cotton and soybean have become dominant in those countries where their planting is p...

Celiac disease, and, more generally, gluten intolerance, is a growing problem worldwide, but especially in North America and Europe, where an estimated 5% of the population now suffers from it. Symptoms include nausea, diarrhea, skin rashes, macrocytic anemia and depression. It is a multifactorial disease associated with numerous nutritional deficiencies as well as reproductive issues and incre...

Transgenic glyphosate-resistant crops (GRCs) have been commercialized and grown extensively in the Western Hemisphere and, to a lesser extent, elsewhere. GRCs have generally become dominant in those countries where they have been approved for growing. Potential effects of glyphosate on soil and water are minimal, compared the effects of the herbicides that are replaced when GRCs are adopted. Pe...

Weed management systems in almost all Brazilian coffee plantations allow herbicide spray to drift on crop plants. In order to evaluate if there is any effect of the most commonly used herbicide in coffee production, glyphosate, on coffee plants, a range of glyphosate doses were applied directly on coffee plants at two distinct plant growth stages. Although growth of both young and old plants wa...

Pseudomonas sp. strain PG2982 has the ability to use the phosphonate herbicide, glyphosate, as a sole phosphorus source (J. K. Moore, H. D. Braymer, and A. D. Larson, Appl. Environ. Microbiol. 46:316-320, 1983). Glyphosate uptake is maximal in the late log phase of growth and is induced by phosphate starvation. Uptake is inhibited by phosphate and arsenate, but not by the amino acids glycine an...

Objective: Importance of management of gardens weeds is an issue that unfortunately has less been investigated by weeds researchers of country. One of the most important restrictive agents of cultivated surface and producing crops of Citrus orchards are weeds. Methods: To achieve this purpose, a research was performed in plot of Valencia orange trees of citrus fruits of Dezful in 2013. This pro...

Greenhouse and field studies were conducted to evaluate potential interactions between glyphosate and trifloxysulfuron on barnyardgrass, browntop millet, hemp sesbania, seedling john­ songrass, pitted morningglory, prickly sida, sicklepod, and velvetleaf control as well as cotton injury and yield. In the greenhouse, glyphosate at 840 g ae/ha controlled all weed species 62 to 99%, which was bett...

Glyphosate, a broad spectrum herbicide widely used in agriculture all over the world, inhibits 5-enolpyruvylshikimate-3-phosphate synthase in the shikimate pathway, and glycine oxidase (GO) has been reported to be able to catalyze the oxidative deamination of various amines and cleave the C-N bond in glyphosate. Here, in an effort to improve the catalytic activity of the glycine oxidase that wa...