BACKGROUND AND AIMS  Capsule endoscopy (CE) has revolutionized small-bowel (SB) investigation. Computational methods can enhance diagnostic yield (DY); however, incorporating machine learning algorithms (MLAs) into CE reading is difficult as large amounts of image annotations are required for training. Current databases lack graphic annotations of pathologies and cannot be used. A novel databas...

The Sneaky Kid and Its Aftermath is a first-person account of the (sexual) intimacy between a researcher (Harry WOLCOTT) and his research participant (Brad, the sneaky kid). Two years after the events, the sneaky kid returned with a vengeance, beating up the researcher and burning down his house. Autobiographical texts may lead readers to confuse author and literary figure of the same name. Any...

The Cip/Kip protein family, which includes p27, p21, and p57, modulates the activity of cyclin-dependent kinases (Cdks). A domain within these proteins, termed the kinase inhibitory domain (KID), is necessary and sufficient for Cdk inhibition. The KID consists of a cyclin-binding subdomain (termed D1) and a Cdk-binding subdomain (termed D2) joined by a 22-residue linker subdomain (termed LH). B...

We recently described a pair of ligands, PPKID4(P) (4(P)) and PPKID6(U) (6(U)), which present the alpha-helical functional epitope found on helix B of the CREB KID activation domain (KID(P)) on a pancreatic fold protein scaffold. 4(P) and 6(U) bind the natural target of KID(P), the KIX domain of the coactivator CBP, with equilibrium dissociation constants between 515 nM and 1.5 microM and compe...

Zinc finger proteins of the Cys2His2 class represent a large group of DNA-binding proteins. A major subfamily of those proteins, the Krüppel-associated box (KRAB) domain-containing Cys2His2-zinc finger proteins, have been described as potent transcriptional repressors. So far, however, no DNA-binding sites for KRAB domain-containing zinc finger proteins have been isolated. Using a polymerase ch...

BACKGROUND The prevalence of Campylobacter jejuni and Campylobacter coli was determined in goat and goat meat sold at retail outlets in Lubumbashi, Democratic Republic of Congo (DR Congo). METHODOLOGY A total of 644 samples, including 177 goat meat, 86 goat stomachs, 139 ready to eat (RTE) goat skewers, and 242 goat faecal samples were examined for the presence of Campylobacter jejuni and Cam...

BACKGROUND Goat milk production in Shaanxi province is dominant in China, but the product is mainly infant formula and adult milk powder; product homogeneity is serious and has no goat yoghurt with probiotic culture. METHODS The effect of bacteria proportion (1:3:1, 1:2:1, 1:1:1, 2:1:1, 3:1:1) on pH, acidity, and viable counts and sensory evaluation of goat milk fermented by probiotics includ...

the objective of this research was to discriminate four local breeds of goat in central java-indonesia using multivariate analysis. data from eight morphological traits of four goat breeds, namely kejobong goat (jg), etawa grade goat (egg), kacang goat (kg) and jawarandu goat (rg) originated from purbalingga, purworejo, grobogan and pemalang regencies, respectively, were used. one hundred and s...

The objective of this research was to discriminate four local breeds of goat in Central Java-Indonesia using multivariate analysis. Data from eight morphological traits of four goat breeds, namely Kejobong goat (JG), Etawa Grade goat (EGG), Kacang goat (KG) and Jawarandu goat (RG) originated from Purbalingga, Purworejo, Grobogan and Pemalang regencies, respectively, were used. One hundred and s...