Huntington's disease (HD) is a progressive neurodegenerative disorder caused by trinucleotide repeat (TNR) expansions. We show here that somatic TNR expansions are significantly reduced in several organs of R6/1 mice lacking exon 2 of Nei-like 1 (Neil1) (R6/1/Neil1(-/-)), when compared with R6/1/Neil1(+/+) mice. Somatic TNR expansion is measured by two different methods, namely mean repeat chan...

Four US genetic-economic indices for dairy cattle were retrofitted to illustrate differences in phenotypic response observed for retrospective selection over 2 generations for currently evaluated traits, even though producers did not have evaluations available at the time for direct selection for those traits. Differences among cows were compared based on ranking of their sires and maternal gra...

BACKGROUND Available evidence suggests that 50% of couples with infertility are male related. Over 40% of these males consume alcohol which has been reported to be a reproductive toxicant causing depletions in the epithelium of seminiferous tubules hence reducing sperm counts and sperm morphology. OBJECTIVE To determine the effects of aqueous leaf extract of Telfairia occidentalis on alcohol-...

BACKGROUND Growing evidence suggests that abdominal obesity is a more important risk factor for the prognosis of cardiovascular and metabolic diseases than BMI. Somatic-affective symptoms of depression have also been linked to cardiovascular risk. The relationship between obesity and depression, however, has remained contradictory. Our aim was therefore to relate body mass index (BMI) and diffe...

This study investigated pre-competition physiological and psychological states of eighteen elite soccer players. Salivary cortisol was assessed during a non- training day and before three league games. Affective states (unpleasant and pleasant, somatic and transactional emotions) were evaluated using the Tension and Effort-Stress Inventory before the three league games. Participants formed 2 gr...

The study object was an Odontesthes bonariensis (Valenciennes, 1835) population of a characteristically shallow lake from the pampasic region. Over one year, zooplankton and fish samples were collected monthly. As a function of time and gender, several indices were investigated (relative weight, mesentery fat index, gonadosomatic index, hepatosomatic index and somatic index) and were related to...

The temperature–humidity index (THI) has been commonly used to analyse heat stress in dairy cattle, but little is known about its effects on buffaloes. In this study, daily milk yield (MY), fat percentage (FP), protein (PP) and somatic cell count (SCC) data from 808 buffalo cows plus environmental temperature relative humidity were investigate the consequence of stress. Two mixed models evaluat...

the objective of this study was to analyze the association of somatic cell score (scs) with milk, fat and protein yields across parities. records of production traits and somatic cell counts (scc) from first, second and third parity that were collected by the animal breeding center of iran from 1993 to 2010 were used.all animals were grouped into six classes according to scc and production trai...