Epidermal growth factor (EGF) in rat salivary glands is regulated by testosterone, thyroxin, and growth hormone (GH). Salivary glands of 45-day-old giant and dwarf male and female transgenic mice were examined histologically and by immunohistochemistry (IHC) for EGF. Male giants showed no significant differences from wild-type (WT) parotid and submandibular glands. However, their sublingual gla...

BACKGROUND: Malignant granular cell tumor (MGCT) is a rare disease entity. Forty-one well-documented MGCTs have been reported in the world literature. CASE REPORT: This report describes a patient who presented with a MGCT of the lung and reviews the preoperative evaluation, pathologic features and differential diagnosis of the disease. This case represents the first report of resected primary p...

With the polarimetric observations obtained by the Spectro-Polarimeter on board Hinode, we study the relationship between granular development and magnetic field evolution in the quiet Sun. 6 typical cases are displayed to exhibit interaction between granules and magnetic elements, and we have obtained the following results. (1) A granule develops centrosymmetrically when no magnetic flux emerg...

A 53-year-old woman complaining of vertical diplopia, presented with a localized swelling in the right lower lid. Magnetic resonance imaging studies demonstrated a relatively well-defined mass in the inferior rectus with similar signal characteristics to the muscle. Excisional biopsy of the mass revealed granular cell tumor composed of S-100 positive cells with acidophilic granular cytoplasm an...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Hybrid peripheral nerve sheath tumors (PNSTs), which show hybrid features of more than one ...

A 53 year-old woman presented with a slowly progressive, painless proptosis OS. Computed tomography disclosed a round, homogeneous, well-delimited lesion in the inferior-temporal orbit. The tumor was composed of round cells with eosinophilic granular cytoplasm. Some of the cells had larger eosinophilic granules surrounded by a clear halo; known as pustulo-ovoid bodies of Milian or Bangle bodies...

1Servicio de Citometría & Departamento de Medicina, Universidad de Salamanca, Salamanca, Spain; 2Instituto de Biología Molecular y Celular del Cáncer, Centro de Investigación del Cáncer/Universidad de Salamanca/Consejo Superior Investigaciones Cientificas, Salamanca, Spain; 3Servicio de Análisis Clínicos, Hospital Universitario Virgen de las Nieves, Granada, Spain; 4Unidad de Investigación, Ins...

BACKGROUND Granular cell tumors are benign lesions that typically occur in the oral cavity, but can also be found in other sites. However, the characteristics of these tumors are unclear. Thus, the present study aimed to investigate the immunohistological characteristics of these tumors of the tongue. METHODS Seven patients were treated for granular cell tumors of the tongue at our institutio...

We unravel how mechanical stress heterogeneity and core-periphery asymmetry in tissue spheroids are modulated by their granular micro-structure, means of simulations with a deformable cell model.