Cyclops are among the best-known monsters of Greek mythology, also mentioned in art and literature. According to the most recent scientific knowledge, the malformations caused by defective development of the anterior brain and midline mesodermal structures include cyclopia (synophthalmos), ethmocephaly, cebocephaly and arrhinencephaly. These severe forebrain lesions often are accompanied by sev...

Interleukin-6 (IL-6) is a key player in inflammation and the main factor for the induction of acute phase protein biosynthesis. Further to its central role in many aspects of the immune system, IL-6 regulates a variety of homeostatic processes. To interfere with IL-6 dependent diseases, such as various autoimmune diseases or certain cancers like multiple myeloma or hepatocellular carcinoma asso...

In Greek mythology, Procrustes was a rogue smith and bandit who invited travellers to rest in his “perfectly sized bed.” When they accepted, he forcibly bound them to it, then stretched them or cut off various body parts until they “perfectly” fit the bed. Too many organizations have a single model of high maturity to which they try to fit all their projects. Development and acquisition organiz...

During the past 30 years orthotopic liver transplantation has become a highly successful form of surgical treatments. The significant advances achieved in this field have led to an increased demand for organs and created a wide gap between organ availability and organ supply. A wider availability of organs for transplantation would allow an expansions rather than a contraction of the indication...

Different types of alcoholic beverages such as wine and beer were used in ancient times for various medicinal purposes. Being the oldest and probably the most widely used drugs, they were known to have some therapeutic value, in addition to the vital part they played in the daily life of people. Ethanol is produced by fermentation of a variety of plants and consumed either in a diluted form or ...

Traditional inflationary approaches that specify the nature of truth are attractive in certain ways; yet, while many of these theories successfully explain why propositions in certain domains of discourse are true, they fail to adequately specify the nature of truth because they run up against counterexamples when attempting to generalize across all domains. One popular consequence is skepticis...

Development and homeostasis of multicellular organisms relies on an intricate balance between cell proliferation and differentiation. Geminin regulates the cell cycle by directly binding and inhibiting the DNA replication licensing factor Cdt1. Geminin also interacts with transcriptional regulators of differentiation and chromatin remodelling factors, and its balanced interactions are implicate...

Acknowledgements I would like to thank some people who were involved in the creation of this thesis: • Berry Schoenmakers of TU Eindhoven for introducing me to the topic of cryptographic voting protocols. • Evangelos Karatsiolis for his work in guiding me through the process of writing this thesis and his constant motivation. • Roberto Samarone Araujo for hours of discussing various protocols w...

The quest for immortality has long fascinated mankind. According to Greek mythology, ambrosia was the elixir of gods, bestowing them with immortality. Alchemists sought the mystical philosopher’s stone, and Oscar Wilde’s Dorian Gray bequeathed his soul to stop himself from growing old. F. Scott Fitzgerald’s Benjamin Button was all too familiar with the term ‘‘reverse aging.’’ While biblical sou...

This article aims to describe important points in the history of panic disorder concept, as well as to highlight the importance of its diagnosis for clinical and research developments. Panic disorder has been described in several literary reports and folklore. One of the oldest examples lies in Greek mythology – the god Pan, responsible for the term panic. The first half of the 19th century wit...