نتایج جستجو برای: guinea
تعداد نتایج: 34390 فیلتر نتایج به سال:
Effects of R[+]-8-([1-[3,4-dimethoxyphenyl]-2-hydroxyethyl]amino) -3,7-dihydro-7-[2-methoxyethyl]-1,3-dimethyl-1H-purine-2,6-dione (MKS-492), a reported type III isozyme inhibitor of cyclic nucleotide phosphodiesterase, on antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats were investigated. 1) MKS-492 inhibited antigen-induce...
We previously developed optimized DNA vaccines against both Lassa fever and Ebola hemorrhagic fever viruses and demonstrated that they were protective individually in guinea pig and nonhuman primate models. In this study, we vaccinated groups of strain 13 guinea pigs two times, four weeks apart with 50 µg of each DNA vaccine or a mock vaccine at discrete sites by intradermal electroporation. Fi...
Guinea pigs and rats are both common animal models for hyperlipidemia studies. However, many recent studies have suggested that rats do not develop hypertriglyceridemia in response to cholesterol feeding. In the present work, the differences in triglyceride metabolism between guinea pigs and rats were investigated. Feeding a high-fat diet containing 0.1% cholesterol and 10% lard for 4 weeks led...
Rejection of bitter substances is common in many species and may function to protect an animal from ingestion of bitter-tasting toxins. Since many plants are bitter, it has been proposed that high tolerance for bitterness would be adaptive for herbivores. Earlier studies conducted on herbivorous guinea pigs (Cavia porcellus) have been used to support this proposal. We tested guinea pigs with bi...
The effectiveness of the antiviral agent ganciclovir (9-[1,3-dihydroxy-2-propoxymethyl]guanine) against guinea pig cytomegalovirus was tested in vitro in guinea pig embryonic fibroblasts and in vivo in an experimental guinea pig cytomegalovirus labyrinthitis model. In vitro, ganciclovir completely prevented guinea pig cytomegalovirus infection of guinea pig embryonic fibroblasts at concentratio...
An immune response (fluorescent antibody to membrane antigen) was detected in guinea pigs inoculated with varicella-zoster virus (VZV) adapted to guinea pig embryonic cells, including the Oka vaccine strain, even when inoculation was by an external route, i.e., nasal or corneal. Live or UV-inactivated virus having the same virus titer before irradiation was administered to guinea pigs by the co...
The microhylid genus Oreophryne reaches its greatest diversity in the New Guinea region, where more than 60 species have been documented to date. Most are small (<30 mm SVL) and only three species, O. anthonyi , idenburgensis inornata exceed 40 SVL adult body size. Here we describe a fourth large of that was collected 1998 from mountains Papua Province western Guinea. In having cartilagi...
This study aimed to identify undesirable and toxic effects of plants used in Guinean traditional medicine. Materials Methods: We surveyed 131 practitioners 2 prefectures Guinea about their knowledge experience with adverse or events associated the medicinal non-medicinal use plants, collecting samples these for botanical analysis. Results: Ethnobotanically, 54 species from 33 families were iden...
The landscape of international event-based biosurveillance David Hartley, Noele Nelson, Ronald Walters, Ray Arthur, Roman Yangarber, Larry Madoff, Jens Linge, Abla Mawudeku, Nigel Collier, John Brownstein, Germain Thinus & Nigel Lightfoot To cite this article: David Hartley, Noele Nelson, Ronald Walters, Ray Arthur, Roman Yangarber, Larry Madoff, Jens Linge, Abla Mawudeku, Nigel Collier, John B...
Values of binary mutual diffusion (interdiffusion) coefficients, obtained by using the Taylor dispersion method, for aqueous solutions of γ-cyclodextrin in the concentration range from (0.002 to 0.010) mol ·dm and temperatures (298.15 and 310.15) K are reported. From these experimental results, the hydrodynamic radius values for the γ-cyclodextrin are estimated. Also, the measured diffusion coe...
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