etoposide, a widely used anticancer drug, exhibits low and variable oral bioavailability mainly because of being substrate for the efflux transporter, p-glycoprotein (p-gp). therefore, the present study was aimed to investigate the effect of d-α-tocopherol polyethylene glycol 1000 succinate (tpgs) and peg 400 as p-gp inhibitors on the intestinal absorption of etoposide. everted sacs of rat smal...

the aim of this study was to evaluate the effect of dietary euphorbia hirta and an acidifier mixture supplementation on gut morphology and some blood parameters of broiler chickens.a total of 240 day old male broiler chicks were randomly assigned to one ofthe four dietary treatment groups including: (1) basal diet (control), (2) basal diet + 7.5 g/kg e. hirta (eh7.5), (3) basal diet + 1.5 g/kg ...

due to the presence of polyphenols and phthalides in kelussia odoratissima mozzaf (umbelliferae; k. odoratissima hereafter), this medicinal plant might be a robust in-feed additive to modulate lipid peroxidation in meat-type chickens. the present study evaluates antioxidative, antihyperlipidemic, and growth-promoting effects of k. odoratissima in meat-type chickens. in a 37-day trial (5-42 days...

the experiment was conducted to determine α-amylase activity and the effect of seven plant species extracts including punica granatum l. (punicaceae), rheum officinale b. (polygonaceae), rhus coriaria l. (anacardiaceae), artemisia sieberi b. ( compositae), peganum harmala l. (nitrariaceae) , datura stramonium l. (solanaceae) and thymus vulgaris l. (lamiaceae) on α-amylase activity of four store...

OPEN ACCESS This open-access article is distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC) (http:// creativecommons.org/licenses/by-nc/4.0/), which permits reuse, distribution and reproduction of the article, provided that the original work is properly cited and the reuse is restricted to noncommercial purposes. For commercial reuse, contact reprin...

the effects of dietary supplementation of grape seed extract (gse) and vitamin c on carcass characteristics, gut morphology and ileal microflora in broiler chickens exposed to chronic heat stress were examined. experimental diets included a control diet (without additive), 3 levels of gse (150, 300, 450 mg/kg of diet), and vitamin c (300 mg/kg of diet). each of the five diets was fed to 5 repli...

amino acids (aa) are important in poultry nutrition not only for protein deposition, but also for other metabolic functions; such as improving immune and gut functions. although, some table values are available on amino acids requirement, aa requirements may vary due to changes in dietary composition and breeding selection. thus amino acids requirements have remained an ongoing research topic. ...

corophium volutator (pallas) has been recommended by the paris commission as one of the standard species for testing chemical used in offshore oil and gas exploration/production. in the present study, gut contents of corophium volutator have been analysed by electron probe microanalysis (epma) for baso4 and other heavy metal impurities after exposure tto spiked sediments following a standard as...

ten female lambs of 7-month-old were divided into two equal groups and raised under a helminth-free conditions. animals in group 1 were immunized two times by whole gut homogenate (wgh) of haemonchus contortus emulsified in freund’s adjuvant. in group 2 (control), animals were injected by phosphate buffered saline emulsified in the same adjuvant. animals were challenged by 10000 third-stage lar...