BACKGROUND The filamentous fungus Aspergillus niger is widely exploited as an important expression host for industrial production. The glucoamylase high-producing strain A. niger CICC2462 has been used as a host strain for the establishment of a secretion expression system. It expresses recombinant xylanase, mannase and asparaginase at a high level, but some high secretory background proteins i...

BACKGROUND Infectious Bursal Disease Virus (IBDV) causes a highly immunosuppressive disease in chickens and is a pathogen of major economic importance to the poultry industry worldwide. The VP2 protein is the major host-protective immunogen of IBDV and has been considered as a potential subunit vaccine against the disease. VP2 coding sequence was cloned in an inducible fungal vector and the pro...

BACKGROUND Considering that the costs of cellulases and hemicellulases contribute substantially to the price of bioethanol, new studies aimed at understanding and improving cellulase efficiency and productivity are of paramount importance. Aspergillus niger has been shown to produce a wide spectrum of polysaccharide hydrolytic enzymes. To understand how to improve enzymatic cocktails that can h...

Twelve isolates of Trichoderma (six of T. harzianum, five of T. viride, one of T. virens), which reduced variably the incidence of collar rot disease caused in peanut by Aspergillus niger Van Tieghem, were evaluated for their potential to produce lytic enzymes during in vitro antagonism. T. viride 60 inhibited highest (86.2%) growth of test fungus followed by T. harzianum 2J (80.4%) at 6 days a...

D-Galacturonic acid, the main monomer of pectin, is an attractive substrate for bioconversions, since pectin-rich biomass is abundantly available and pectin is easily hydrolyzed. l-Galactonic acid is an intermediate in the eukaryotic pathway for d-galacturonic acid catabolism, but extracellular accumulation of l-galactonic acid has not been reported. By deleting the gene encoding l-galactonic a...

This study shows that some species of fungi are affected by the magnetic field, which should be taken into account in studies airborne fungal and air quality. The aim this paper was to evaluate effect oscillating field (OMF) on behavior colonies three genus growth different culture mediums. stains were: Aspergillus niger, Cladosporium cladosporioides Penicillium citrinum were inoculated 90 mm P...

Among the 5-membered nitrogen heterocycles, the privileged scaffolds thiazole and 1,3,4-oxadiazole have been incorporated in a single molecular framework to explore new potential antimicrobial agents. The newly synthesized compounds 5a-l have been synthesized and characterized by IR, H and C NMR spectroscopy and mass spectrometry. The structures of the synthesized compounds are in full agreemen...

Mixed ligand complexes of bivalent metal ions, viz; Co(II), Ni(II), Cu(II) and Zn(II) of the composition (ML1L2) in 1:1:1 molar ratio, (where L1=diphenylamine-2-mercapto-2’-carboxylic acid (DPMC) and L2=2-furyl glyoxalanthranilic acid (FGAA) have been synthesized and characterized by repeated melting point determination, elemental analyses, IR, H-NMR, magnetic susceptibility measurements and el...

Conidial germination is fundamentally important to the growth and dissemination of most fungi. It has been previously shown (K. Hayer, M. Stratford, and D. B. Archer, Appl. Environ. Microbiol. 79:6924-6931, 2013, http://dx.doi.org/10.1128/AEM.02061-13), using sugar analogs, that germination is a 2-stage process involving triggering of germination and then nutrient uptake for hyphal outgrowth. I...

Rickettsia africae, a recently identified pathogen, was detected for the first time in Amblyomma ticks from Niger, Mali, Burundi, and Sudan, and "R. mongolotimonae" was identified for the first time in Africa. Rickettsiae of unknown pathogenicity and two new ehrlichiae of the Ehrlichia canis group were identified in ticks from Mali and Niger.