AbstractBackground The aim of this study was to investigate the incidence and risk factors primary secondary liver failure after major resection for perihilar cholangiocarcinoma. Methods All patients who underwent a presumed cholangiocarcinoma between 2000 2020 at 2 tertiary-referral hospitals were included. Liver defined according International Study Group Surgery cr...

SummaryBackground Most patients with facial pigmentary disorders have multiple disorders. However, there is no definitive treatment algorithm improving various simultaneously. Objectives To investigate the clinical efficacy and safety of combination Q-switched alexandrite carbon dioxide lasers ZO SKIN HEALTHⓇ for Patients/methods This prospective o...

The effects of acute and repeated intraparaventricular (iPVN) administration of human relaxin-3 (H3) were examined on food intake, energy expenditure, and the hypothalamo-pituitary thyroid axis in male Wistar rats. An acute high dose iPVN injection of H3 significantly increased food intake 1 h post-administration [0.4+/-0.1 g (vehicle) vs 1.6+/-0.5 g (180 pmol H3), 2.4+/-0.5 g (540 pmol H3) and...

Objectives To examine in depth carers’ views and experiences of the delivery patient care for people with dementia or delirium an acute general hospital, order to evaluate a specialist Medical Mental Health Unit (MMHU) compared standard hospital wards. This qualitative study complemented quantitative findings randomised controlled trial. Design Qualitative semistructured inter...

AbstractObjectives To systematically review and synthesize the evidence on differential associations between antihypertensive medication (AHM) classes risk of incident dementia. Design Systematic random effects frequentist network meta-analysis. Embase, MEDLINE, Cochrane library were searched from origin to December 2019. Setting participants Randomized contr...

Context. The type and level of healthcare services required to address the needs older adults living with major neurocognitive disorders (MNCD) fluctuate over disease progression while being complexified by multimorbidity inequality factors. Thus, their trajectories care (TC - pattern use time) may vary significantly. Objective. We aimed 1) Propose a typology TC people MNCD; 2...

Importance The 2014 US Preventive Services Task Force (USPSTF) recommendation statement supported the effectiveness of screening for chlamydia and gonorrhea in asymptomatic, sexually active women 24 years or younger older at increased risk infection, although evidence men was insufficient. Objective To update USPSTF review on chlamydial gonococcal infection adults adolescents,...

AbstractObjectives To investigate whether participation in sport during the developmental stages of life is associated with cardiorespiratory fitness (CRF) adulthood. Design Observational longitudinal study. Methods Participants were Generation 2 Raine Study. Questionnaires related to administered at ages 5, 8, 10, 14 and 17 years. These data used develop sex...